tues 25

Question 1

name the 2nd gen antipsychotics?

Answer 1

Olanzapine, Quetiapine, Aripiprazole, Ziprasidone, Risperidone, Clozapine

Question 2

2nd gen antipsychotics are better at treating what than the 1st gen?

Answer 2

the negative symptoms of schizophreni

Question 3

2nd gen antipsychotics are more likely to cause which side effects?

Answer 3

Metabolic - dyslipidemias, weight gain, metabolic syndromes, etc.

Question 4

2nd gen antipsychotics are less likely to cause which side effects?

Answer 4

the antimuscarinic side effects

Question 5

which 2nd gen antipsychotic is associated with myocarditis and cardiomyopathy?

Answer 5

clonazapine

Question 6

name the low potency first gen antipsychotics?

Answer 6

chlorpromazine, thioridazine

Question 7

which side effects are more likely to be caused by low potency than high potency FIRST gen antipsychotics?

Answer 7

• antimuscarinic
• orthostatic hypotensino
• anti-histamine effects

Question 8

which side effects are more likely to be caused by HIGH potency than LOW potency FIRST gen antipsychotics?

Answer 8

the extrapyramidal side effects, galactorea and impotence and neuroleptic malignant sydrome

Question 9

which disease is associated with increased PATERNAL age of the FATHER?

Answer 9

achondroplasia

Question 10

what is the trinucleotide repeat seen in myotonic dystrophy?

Answer 10

CTG

Question 11

HLAB27 =

Answer 11

ankylosing spondylitis

Question 12

HLAB8 =

Answer 12

graves disease

Question 13

HLA B51 =

Answer 13

behcet syndrome

Question 14

what is behcet syndrome?

Answer 14

disease characterize by blood vessels inflammation

Question 15

presentation of behcet syndrome?

Answer 15

• arhtritis
• enthesitis
• vasculitis throughout body
• skin lesinos

Question 16

pathophys of achondroplasia?

Answer 16

constituitively active FGF 23 impairs chondrocyte proliferation and differentation

Question 17

HLADQ1 =

Answer 17

pemphigus vulgaris

Question 18

HLA DR3 =

Answer 18

graves

Question 19

HLA DR5 =

Answer 19

hashimotos

Question 20

antidote to iron toxicity?

Answer 20

deferoxamine

Question 21

antidote for lead toxicity?

Answer 21

succimer

Question 22

flattened t waves =

Answer 22

hypokalemia

Question 23

peaked t waves=

Answer 23

hyperkalemia

Question 24

which disease has rosenthal fibers?

Answer 24

pilocytic astrocytoma

Question 25

which disease has smudge cells?

Answer 25

CLL

Question 26

t(2:5)

Answer 26

anaplastic large cell lymphoma

Question 27

t(11;14)

Answer 27

mantel cell lymphoma

Question 28

whta does the tubomamillary nucleus make?

Answer 28

histamine

Question 29

u waves =

Answer 29

hypokalemia

Question 30

chediak higashi has defective. ..

Answer 30

microtubules

Question 31

which gene is dysfunctional in chediak higashi?

Answer 31

the lyst gene

Question 32

NADPH oxidase forms..

Answer 32

superoxide

Question 33

patients with CGD can still produce

Answer 33

hydroxide radicals (OH-) so can kill some organisms but cant kill catalase positive organisms which can break down OH-

Question 34

neutrophil adhesion deficiency is missing what substance?

Answer 34

CD18