Sun Aug 2

Question 1

whcih immunodeficieny involves chronic loose stools? (diarrhea)

Answer 1

SCID

Question 2

Presentation of SCID?

Answer 2

• several bacteria & viral infections in infancy
• mucocutaneous candiadiasis
• chronic diarhea

Question 3

Clinical findings of SCID?

Answer 3

• low or absent CD3 t cells
• hypogammaglobulinemia
• thymic hypoplasia or aplasia

Question 4

X linked (brutons) agammaglobulinemia is an immunodeficiency that results in insufficient production of what?

Answer 4

Mature B cells

Question 5

are t cells normal in X linked (brutons) agammaglobulinemia ?

Answer 5

yes -thymus is fine. Will have thymic shadow

Question 6

what causes wiskott-aldrich syndrome?

Answer 6

abnormal cytoskeleton functioning resulting in abnormal t and b cells

Question 7

presentation of wiskott-aldrich syndrome?

Answer 7

• reccurent infections, gets worth with age
• easy bleeding
• eczema

Question 8

why are highly lipophilhic drugs poorly eliminated by the kidneys?

Answer 8

they can readily cross the tubules to be reabsorbed

Question 9

why are highly lipophilic drugs better eliminated by the liver?

Answer 9

they can easily cross cellular barriers and enter the hepatocytes, to be excreted in bile, etc.

Question 10

Severe diarhhea results in substantial loss of..

Answer 10

bicarb

Question 11

what is donepezil?

Answer 11

Ach esterase inhibitor - increases Ach - used in alzheimers

Question 12

Cardiac A/E of donepezil?

Answer 12

Donepezil increases your PNS activity, and may precipitate bradycardia and heart block in older patients (age related degeneration of the conduction system) ->decreased CO and syncope

Question 13

what type of bacteria is bacterioides?

Answer 13

Gram negative anearobic rods

Question 14

what muscles inserts onto the greater trochanter?

Answer 14

gluteus medius and gluteus minimus

Question 15

what muscle inserts onto the lesser trochanter?

Answer 15

illiopsoas

Question 16

inheritance of androgenetic alopecia?

Answer 16

polygenic

Question 17

how do aminoglycosides distribute in the body?

Answer 17

Large charged molecule - limited to extracellular space

Question 18

what will the cardiac index be initially in someone with distributive shock (sepsis)?

Answer 18

CI is increased - pumps harder to make up for hypotension

Question 19

what will the mixed venous saturation O2 of the blood be in someone with distributive shock?

Answer 19

Increased - the fast flow rates from increased CI prevents complete extraction of oxygen from tissues

Question 20

does renal tubular acidosis cause normal anion gap or increased anion gap metabolic acidosis?

Answer 20

normal anion gap acidosis