sun aug 10 Flashcards

(45 cards)

1
Q

what is a risk factor for corticosteroid-induced psychosis?

A

hypoalbuminemia

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2
Q

which hepatitis virus integrates its DNA into the host cell genome?

A

hep B

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3
Q

how does pulmonary edema effect lung compliance?

A

it causes decreased lung compliance - the edema in the interstitium makes the lungs heavy and stiff

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4
Q

serology findings of diffuse scleroderma?

A

anti-scl-70

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5
Q

serology findings of limited cutaneous scleroderma/CREST?

A

anticentromere

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6
Q

complications of limited cutaneous scleroderma/CREST??

A

pulmonary hypertension

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7
Q

complications of diffuse scleroderma?

A
  • pulmonary fibrosis

- scleroderma renal crisis

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8
Q

what structures are found in the anterior compartment of the lower leg?

A
  • deep peroneal nerve

- anterior tibial artery/veins

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9
Q

what structures are found in the lateral compartment of the lower leg?

A

-superficial peroneal nerve

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10
Q

what structures are found in the deep posterior compartment of the lower leg?

A
  • tibial nerve
  • posterior tibial artery
  • peroneal artery and veins
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11
Q

what is found in the superficial posterior compartment of the lower leg?

A

muslces

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12
Q

what disease does cryptococcus neoformans most commonly cause?

A

meningoencephalitis

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13
Q

finasteride MOA

A

5-alpha reductase inhibitor

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14
Q

etanarcept MOA

A

-decoy receptor for TNF-alpha - may be used in RA refractory to methotrexate

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15
Q

what is triamterene?

A

potassium sparing diuretic that blocks enac

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16
Q

what is amiloride?

A

potassium sparing diuretic that blocks enac

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17
Q

presentation of vit E deficiency?

A
  • neuromuscular problems (polyneuropathy, ataxia, etc.)

- hemolytic anemia

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18
Q

higher levels of fructose,2,6BPG drive which reaction?

A

the conversion of fructose-6-phosphate to fructose1,6biphosphate (glycolysis)

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19
Q

higher levels of fructose,2,6BPG activate which enzyme?

20
Q

high levels of fructose,2,6BPG inhibit which process?

A

gluconeogenesis

21
Q

sorbitol is normally metabolized into what substance?

22
Q

where do the reactions of the pentose phosphate pathway (HMP shunt) occur?

A

both occur in the cytosol

23
Q

where does the enzyme ornithine transcarbomylase act?

24
Q

partial pressure of oxygen represents..

A

the oxygen dissolved in the plasma

25
does carbon monoxide effect the partial pressure of oxygen?
NO
26
PaO2 =
partial pressure of oxygen in plasma
27
what will be seen on autopsy of someone who had tuberculus meningitis?
- thick gelatinous exudate mostly at the basal portion of the brain - multiple bilateral brain infarcts especially in the periventricular areas(from tuberus vasculitis) - hydrocephalus - tuberculosis proteins may cause obstruction
28
what foramina connect the lateral ventricles and the third ventricle?
foramina of monro
29
what does the cerebral aqueduct connect?
the third and fourth ventricles
30
affarent nerve of cough reflex?
10
31
efferent nerve of cough reflex?
10
32
affarent nerve of gag reflex?
9
33
efferent nerve of gag reflex?
10
34
what causes chick pox?
varicella zoster virus
35
on EMB agar, what organisms will produce a green sheen?
those that ferment lactose
36
group A strep virulence factor M protein function?
resist phagocytosis
37
structure of M protein?
alpha helical coiled protein
38
what is the structure of tropomyosin and myosin?
alpha helical coiled protein
39
why is the homology seen between M protein of group A strep and the tropomysosin and myosin in humans important?
protective antibodies may cross react with myosin in the heart leading to rheumatic heart disease
40
how do macrolides affect the GI tract?
they stimulate motilin receptors of the upper GI tract
41
In ataxia telangiectasia, DNA is hypersensitive to..
ionizing radiation
42
presentation of ataxia-telangiectasia?
- ataxia (due to cerebellar atrophy) in first years of life - recurrent sinopulmonary infections - skin telangiectasias later in life - increased risk of cancer
43
presentatino of follicular lymphoma?
-usually follows an indolent coarse with waxing and waning. Lymph node enlargement is painless and may goup and down in size.
44
presentation of diffuse large B cell lymphoma?
-rapidly enlarging nodal and systemic B symptoms
45
reid index =
mucous glands / (submucosa + lamina propria)