sun aug 23 Flashcards

1
Q

innervation to cricothyroid?

A

external branch of superior laryngeal nerve

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2
Q

external branch of superior laryngeal nerve travels with which artery?

A

superior thyroid artery

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3
Q

what does ceftriaxone bind to?

A

transpeptidases

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4
Q

a high salt diet is a risk factor for which cancer?

A

gastric adenocarcinoma

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5
Q

what is HbA2?

A

alpha 2 delta 2

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6
Q

in which thalasemias is there increased HbA2?

A

beta thalasemias

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7
Q

glucocorticoids inhibit…

A

phospholipase A2

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8
Q

what does phospholipase A2 do?

A

produces arachidonic acid from membrane phospholipids

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9
Q

zileuton MOA?

A

inhibits 5-lipooxygenase

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10
Q

what does 5-lipooxygenase do?

A

produces leukotrienes from arachidonic acid

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11
Q

how does montelukast work?

A

blocks binding of leukotrienes to receptors - prevents bronchoconstriction/membrane permeability

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12
Q

how does zafirlukast work?

A

blocks binding of leukotrienes to receptors - prevents bronchoconstriction/membrane permeability

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13
Q

LTB4 function?

A

neutrophil chemotaxis

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14
Q

how does reducing cardiac contractility help treat hypertrophic cardiomyopathy?

A

it reduces the amount of blood ejected during systole, leading to an increased end systolic volume - icnreasedd volume helps prevent obstruction

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15
Q

who typically gets fibromuscular dysplasia?

A

young woman

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16
Q

how does fibromuscular dysplasia present?

A

young woman with hypertension - increased aldosterone due to renal artery involvement.

17
Q

how does polyarteritis nodosa present?

A

vasulitis that may be in various organs. associated with Hep B

18
Q

which has lower pressure, the pulmonary arteries or bronchial arteries?

A

the pulmonary arteries are a LOW pressure system

19
Q

which immunodeficiency is associated with an anaphylatic shock in repsonse to blood transfusion?

A

selective igA deficiency

20
Q

why can selective igA deficiency cause anaphylaxis in response to blood transfusion?

A

blood products may have small amounts of igA, which patients wihtout igA recognize as foriegn. if they have preformed antibodies it can result in anaphylaxis

21
Q

how are the electrolytes effected during the recovery phase of acute tubular necrosis?

A

during this phase there is elecrolyte wasting. At risk for hypokalemia, as well as hypocalcemia etc