Aug 4 NBME Flashcards

1
Q

left hemithorax =

A

left side of the thorax

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2
Q

what are the two types of leprosy?

A
  • Lepromatous

- Tuberculoid

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3
Q

what type of t cell response occurs in lepromatous leprosy?

A

Th2

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4
Q

what kind of t cell response occurs in tuberculoid leprosy?

A

Th1

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5
Q

what is amyloid made of?

A

misfolded aggregates of beta-pleated sheets

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6
Q

helix-loop-helix is an example of..

A

a dna binding motif

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7
Q

what is the first pubertal change in females?

A

breast bud development (shortly followed by pubic hair)

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8
Q

what is the first pubertal change in males?

A

testicular enlargement

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9
Q

how does the protein E6 work?

A

hijacks the cell ubiquitin system and targets p53 for destruction

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10
Q

is staph epidiermidis catalase + or -?

A

catalase +

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11
Q

is enterococcus catalase + or -?

A

catalase -

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12
Q

what type of drug is alendronate?

A

bisphosphonate

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13
Q

what is the suffix of bisphonsphonateS?

A

‘dronate’

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14
Q

bisphosphonates have a chemical structure similar to….

A

pyrophosphate

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15
Q

how does fibrosis effect traction in the lungs?

A

Fibrosis pulls the airways open, increasing radial traction and decreasing resistance to flow

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16
Q

cyclophosphamide MOA

A

Alkylating agent - cross links DNA

17
Q

what is defective in familial type II hypercholesterinemia?

A

defect in liver LDL receptors

18
Q

Cholesterol deposits on he achiles tendons are indicative of…

A

familial type II hypercholesterinemia

19
Q

if someone has intranuclear opthalmoplegia, where is the lesion?

A

ipsilateral medial longitudinal fasciculus

ipsilateral to the eye that cannot adduct

20
Q

how does estrogen effect endogenous cholesterol production?

A

increases it - may increase risk for gallstones

21
Q

which nerve supplies sensation to the lower teeth?

A

inferior alveolar nerve

22
Q

inferior alveolar nerve becomes the…

A

mental nerve

23
Q

A patient has hemiballismus on the right. Where is the brain lesion?

A

Left (contralateral) subthalamic nucleus

24
Q

which clotting factor has the shortest half life?

A

VII

25
Q

4Ds of pellegra?

A

photosensitive dermatitis, diarrhea, dementia, and death.

26
Q

when does the neural tube develop?

A

weeks 3 to 8

27
Q

Although gluconeogenesis primarily is performed in the liver, which other organs can perform it as well?

A

intestine

kidneys

28
Q

dantrolene MOA

A

blocks SR release of calcium by binding ryr

29
Q

innervation to the uvula?

A

CN X

30
Q

what is fibromuscular dysplasia?

A

a disease that causes medium sized arteries to have a beads on a string appearance - commonly in renal arteries

31
Q

mallory bodies are seen in which condition?

A

alcoholic hepatitis

32
Q

what are malory bodies

A

intracytoplasmic eosinophilic inclusions of damaged keratin filaments

33
Q

Odss ratio formula?

A

(a/d) / (b/c)