BMS09-1015 Bone Cells Flashcards

1
Q

What is bone

A

Living hard connective tissue protecting organs

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2
Q

What % of bone is mineral?

A

75

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3
Q

What forms matrix?

A

90% type 1 collagen
5% water
5% osteopontin, osteocalcin and other non-collagenous proteins

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4
Q

How many bones are there?

A

206

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5
Q

What is fibrocartilage?

A

Dense collagen 1 fibres added to hyaline matrix

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6
Q

What 2 things are made of elastic cartilage?

A

Auricle of the ear and the larynx

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7
Q

What is elastic cartilage?

A

Elastic fibres added to hyaline matrix

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8
Q

2 examples of hyaline cartilage

A

Ribs

Trachea

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9
Q

How do osteoclasts eat?

A

Lysosomes

Proton pumps

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10
Q

What connects osteocytes?

A

Canaliculi gap junctions

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11
Q

What shape are osteoblasts?

A

Cuboidal

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12
Q

What do osteoblasts make?

A

Osteoid

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13
Q

Structure of GAG’s

A

Brush like

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14
Q

Matrix proteins of bone (5)

A
Type 1 collagen
Osteocalcin
Osteonectin
Osteopontin
Proteoglycans
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15
Q

Proteoglycans

A

Regulation of collagen fibril formation and mineralisation

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16
Q

Osteopontin

A

Attaches cells to matrix

17
Q

Osteonectin

A

Calcium binding

18
Q

Osteocalcin

A

Bone specific calcium binding

19
Q

Does woven or lamellar bone have more cells?

A

Woven

20
Q

Where is cortical and trabecular bone?

A

Cortical outside trabecular inside