BMS02-1001 Cell Specialisation Flashcards
What is an integral protein?
Goes through both sides of the membrane
Give an example of a peripheral protein
Goes through only one side of the membrane
Give an example of a transporter protein
Actively pumps Na and K in and out of the cell
Give an example of an anchor protein
Integrins link intracellular actin filaments to extracellular matrix proteins
Give an example of the cell membrane enzyme
Adenylyl cyclase which produces cAMP
What is the nucleus composed of?
Chromatin, nucleolus, nuclear envelope
What does the nucleolus contain?
DNA in the form of transcriptionally active ribosomes, genes, RNA and proteins
What does the nucleolus do?
rRNA synthesis and regulation of the cell cycle
What’s the purpose of the nuclear envelope?
Act as a selectively permeable membrane
What does the SER do?
Detoxification/joining of noxious substances, lipid/glycogen/steroid metabolism and membrane formation/recycling
What does the RER do?
Protein synthesis and glycoprotein formation
What does the Golgi do?
Receives protein from RER which it packages for transport
Which are the cis and trans side of the golgi
Cis is where they enter and trans is where they exit
What do lysosomes do?
Decompose things using hydrolytic enzymes
What % of lipid cells are occupied by TAG?
90%
what are microfilaments made of?
Actin
What do microfilaments do?
Act as a structural framework and a contractile element
What do intermediate filaments do?
Structural role
What do microtubules do?
Give the cell shape and act as tracks for organelles movement
What are the 2 protein types in microtubules?
Dynein and kinesin
Which direction does dynein move towards
The - end of the microtubule
What maintains the shape of microvilli?
Actin filaments anchored to the action cortex
What has the 9+2 arrangement?
Cilia
What protein makes up microtubules?
Tubulin