BMS08-1006 Soft Connective Tissue

Question 1

Which occupies more space the ECM or cells?

Answer 1

ECM

Question 2

What is SCT?

Answer 2

Cells in ECM

Question 3

What makes ECM?

Answer 3

The cells

Question 4

What can SCT contain?

Answer 4

Mast cells 
Capillaries 
Elastic fibres 
Collagen 
Fibroblasts 
Proteoglycans 
Glycoproteins
Macrophage

Question 5

What are it’s functions?

Answer 5

Space filler 
Support 
Attachment 
Protection 
Storage 
Immune defence 
GAGs
Path for nutrients

Question 6

Reticular (2)

Answer 6

Bone marrow

Lymph

Question 7

Adipose

Answer 7

Fat cells

Question 8

Dense (3)

Answer 8

Tendon
Dermis
Capsules

Question 9

Loose (2)

Answer 9

Under dermis

Mesentery

Question 10

Mesenchyme

Answer 10

Embryonic

Question 11

Which important proteins do fibroblasts secrete? (3)

Answer 11

Collagen
Elastin
Adhesive proteins

Question 12

Where is type 3 collagen?

Answer 12

Blood vessels and skin

Question 13

What is type 5 collagen?

Answer 13

Sheet collagen e.g. BM

Question 14

What type of CT is collagen involved in?

Answer 14

Dense

Question 15

What can surround a core of cross linked elastin?

Answer 15

Microfibrils

Question 16

Which fibroblasts make elastin?

Answer 16

Embryonic and juvenile

Question 17

What receptor proteins cross link cells?

Answer 17

Integrins

Question 18

What ECM proteins to integrins bind? (3)

Answer 18

Fibrobectin and collagen
Tenasin
Laminin

Question 19

Where is tenasin found?

Answer 19

Wounds

Question 20

Where is laminin found?

Answer 20

BM

Question 21

What does the BM do?

Answer 21

Maintain integrity of tissues

Question 22

What are GAGs?

Answer 22

Sugar polymers of a repeating disaccharide

Question 23

Are GAGs positive or negative?

Answer 23

Negative

Question 24

Can sugar chains be compacted?

Answer 24

No they are too stiff and hydrophilic

Question 25

What sucks water into the GAG matrix?

Answer 25

Osmotically active ion cloud due to negative charge

Question 26

What are proteoglycans?

Answer 26

GAG with a protein

Question 27

Name 3 indigenous cells and which stem cell makes these?

Answer 27

Mast cells Adipocytes Fibroblasts Mesenchymal BUT mast have stem cells in bone marrow

Question 28

How does ECM withstand compression?

Answer 28

The turgor due to water swelling in GAG