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Year 1 Summative 1 > BMS08-1006 Soft Connective Tissue > Flashcards

BMS08-1006 Soft Connective Tissue Flashcards

1
Q

Which occupies more space the ECM or cells?

A

ECM

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2
Q

What is SCT?

A

Cells in ECM

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3
Q

What makes ECM?

A

The cells

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4
Q

What can SCT contain?

A 
Mast cells 
Capillaries 
Elastic fibres 
Collagen 
Fibroblasts 
Proteoglycans 
Glycoproteins
Macrophage
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5
Q

What are it’s functions?

A 
Space filler 
Support 
Attachment 
Protection 
Storage 
Immune defence 
GAGs
Path for nutrients
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6
Q

Reticular (2)

A

Bone marrow

Lymph

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7
Q

Adipose

A

Fat cells

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8
Q

Dense (3)

A

Tendon
Dermis
Capsules

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9
Q

Loose (2)

A

Under dermis

Mesentery

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10
Q

Mesenchyme

A

Embryonic

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11
Q

Which important proteins do fibroblasts secrete? (3)

A

Collagen
Elastin
Adhesive proteins

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12
Q

Where is type 3 collagen?

A

Blood vessels and skin

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13
Q

What is type 5 collagen?

A

Sheet collagen e.g. BM

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14
Q

What type of CT is collagen involved in?

A

Dense

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15
Q

What can surround a core of cross linked elastin?

A

Microfibrils

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16
Q

Which fibroblasts make elastin?

A

Embryonic and juvenile

17
Q

What receptor proteins cross link cells?

A

Integrins

18
Q

What ECM proteins to integrins bind? (3)

A

Fibrobectin and collagen
Tenasin
Laminin

19
Q

Where is tenasin found?

A

Wounds

20
Q

Where is laminin found?

A

BM

21
Q

What does the BM do?

A

Maintain integrity of tissues

22
Q

What are GAGs?

A

Sugar polymers of a repeating disaccharide

23
Q

Are GAGs positive or negative?

A

Negative

24
Q

Can sugar chains be compacted?

A

No they are too stiff and hydrophilic

25
Q

What sucks water into the GAG matrix?

A

Osmotically active ion cloud due to negative charge

26
Q

What are proteoglycans?

A

GAG with a protein

27
Q

Name 3 indigenous cells and which stem cell makes these?

A

Mast cells
Adipocytes
Fibroblasts

Mesenchymal BUT mast have stem cells in bone marrow

28
Q

How does ECM withstand compression?

A

The turgor due to water swelling in GAG

Year 1 Summative 1 (56 decks)

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