Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Year 1 Summative 1 > BMS03-1024 Pharmacology of the SNS > Flashcards

BMS03-1024 Pharmacology of the SNS Flashcards

1
Q

What 2 things may the agonist salbutamol be used to treat?

A

Premature labour and asthma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What can the antagonist propranolol treat?

A

Hypertension

Angina

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Angina

A

Muscles not receiving enough oxygen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Hypertension

A

High BP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What 3 places can drugs attach the systemic NS and what is there effects?

A

Sympathetic nerves- widespread reaction
Nicotinic receptors - non specific
Adrenergic receptor - specific

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What may be targeted post ganglionic?

A

Tyrosine isn’t able to be turned into NA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What 2 things do methyldopa do?

A

Lower BP by stimulating adrenergic receptors

Inhibit enzymes that made dopamine and NA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What does reserpine do?

A

Inhibit ACh reuptake

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What does clonidine do? What can it treat?

A

Blocks adrenergic pre receptors which have a negative feed feedback system so no NA is made

Tachycardia
Hypertension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What does amphetamine do?

A

Compete for the reuptake channel so there is more NA activating receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which receptor does cardiac muscle have?

A

Beta adrenergic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which receptor does smooth muscle have?

A

Alpha adrenergic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What else can take up NT? What happens in this process?

A

Extrasynaptic uptake for metabolism in tissues liver and then urine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What does a2 do? Where does it work?

A

Inhibit NT release

Presynaptic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What does b1 do?

Where does it work?

A

Increase force and frequency of contraction

Postsynaptic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Where does a1 act?

A

Postsynaptic

17
Q

Where does b2 act? What does it mainly cause?

A

Non synaptic sites

Relaxation

18
Q

Sympathomimetics

A

Drugs that mimics the action of endogenous sympathetic NS agents

19
Q

How can adrenaline be used?

A

Cardiac arrest

Acute hypotension

20
Q

How can noradrenaline be used?

A

Cardiac arrest

Acute hypotension

21
Q

What receptors do these act on?

A

A and B

22
Q

Name 2 drugs only alpha selective

A

Clonidine

Phenylephrine

23
Q

Name 2 beta selective

A

Dobutamine

Salbutamol

24
Q

What does salbutamol treat?

A

Asthma

25
Q

3 side affects of B blockers

A

Tired
Risk of cardiac failure
Bronchoconstriction

26
Q

Salbutamol

What does it act on and what does it treat?

A

B2 agonist
Asthma
Premature labour

27
Q

Atenolol

What does it act on and what does it treat?

A

B1 antagonist
Hypertension
Angina

28
Q

Prazosin

What does it act on and what does it treat?

A

A1 antagonist

Hypertension

29
Q

Labetalol

What does it act on and what does it treat?

A

A1/B antagonist

Hypertension

Year 1 Summative 1 (56 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions