Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Year 1 Summative 1 > BMS09-1014 Bone Development > Flashcards

BMS09-1014 Bone Development Flashcards

1
Q

What shape are osteoblasts?

A

Cuboidal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What do osteoblasts do?

A

Form bone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is osteoid?

A

Mineralised bone matrix

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Where are osteoprogenitor cells found?

A

Periosteum on top of osteoblasts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is stroma?

A

Connective tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Where are osteoblasts found?

A

On bone surfaces

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

How do osteocytes communicate?

A

Cannaliculi and gap junctions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Function of lining cells?

A

To prepare the bone surface for resorption

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What were lining cells originally?

A

Osteoblasts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Where are osteocytes found?

A

In lacunae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are volkmanns canals?

A

The things that connect haversian canals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are haversian canals?

A

Carries blood vessels and nerves through the bone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Compare cortical and trabecular bone

A

Cortical is outside trabecular bone and is more compact

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Where do you find haversian canals?

A

Cortical bone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is lamellae bone

A

Remodelled woven bone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is woven bone?

A

Immature bone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is an osteon?

A

Haversion canals surrounded by lamellae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Name the 3 types of lamella

A

Circumferential
Interstitial
Concentric

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Where are osteons?

A

Cortical

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Where are lamellae?

A

Both mature bone types

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Where is hyaline cartilage found?

A

Articular growth plate

Epiphyseal joint

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Where is the periosteum

A

On the edge of the bone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Where is the endosteum?

A

Lining each bone marrow space

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What cells are there lots of in bone marrow?

A

Megakaryocytes
Macrophages
Lipid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Where are the osteo cells found in the endo or peri?

A

Periosteum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

What happens to bone marrow with age?

A

Fills with lots of fat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Where is articular cartilage?

A

At the ends of bones

28
Q

Describe the nuceli of osteoblasts?

A

Multi

29
Q

Which stem cell is the main chondro osteo precursor?

A

Mesenchymal

30
Q

Which osteo cell is made by haematopoietic stem cells?

A

Osteoclasts

31
Q

What do clasts remove and leave?

A

Remove mineral but leave cartilage for hydrolytic enzymes

32
Q

How do clasts eat?

A

Acidification

33
Q

Describe clasts border

A

Ruffled

34
Q

Howships lacuna

A

Erosion of bone due to clasts

35
Q

How do clasts operate?

A

Joins sealing zone and makes ruffled border and releases acid to demineralise it

36
Q

What is a clear zone in an osteoclast?

A

An area with no organelles

37
Q

Endochondral VS intramembranous

A

Not directly from precursors a cartilage intermediate is used

38
Q

Which bones use endochondral?

A

Long bones

39
Q

Which bones use intramembranous?

A

Flat skull bones

40
Q

Describe intramembranous

A 
Bone formed in membrane from precursors 
Periosteum 
Differentiation to osteoblasts 
Mineralisation and matri deposition 
Vascularisation
41
Q

What joins to make the bone plates in intramem?

A

Islands of bone

42
Q

Describe endo ossification

A

Chondroblasts form the perichondrium then it turns into the periosteum
Capillaries invade
Osteoclasts come in
Primary oss centre
Cortical and traberculae bone
Secondary (epihyseal) oss centre (towards the end of the boen)
Growth plate and epiphyseal cartilage

43
Q

Where does endo oss begin?

A

Bony collar

44
Q

What is 1 and 2 spingiosa?

A

Marrow space

45
Q

What type of collagen does the cartilage on mature bone have?

A

Type 2

46
Q

What type of collagen does bone have?

A

1

47
Q

Describe the epiphyseal growth plate from the top

A

Resting
Proliferative
Hypertrophic
Ossifying

48
Q

What does the ossifying centre mean?

A

Calcified

49
Q

What happens in the proliferating zone?

A

Chondroblasts are organised into sacs as they are expanding

50
Q

In which type of ossification are the 2 growth plates found?

A

Endochondral in endochondral

Epiphyseal in intramembranous

51
Q

Describe the endochon growth plate

A

2 ossification centre
Resting zone
Proliferative zone
Calcification zone

52
Q

Which chromatin is active?

A

Euchromatin

53
Q

What do precursors of hypertrophic chondrocytes turn into?

A

Chondrocytes

54
Q

What forms the 1 spongiosa?

A

Cartilage
Woven bone which will be replaced with mature bone
Calcified cartilage waiting to be bone

55
Q

What happens in the 1 spongiosa?

A

Cartilage turns to bone

56
Q

What does mature bone have that woven doesn’t?

A

Sheets of collagen

57
Q

What is absent in secondary spongiosa?

A

Cartilage

58
Q

What happens from the growth plate down?

A

Primary sponge
Secondary
Bone marrow

59
Q

Appositional growth

A

New matrix on old matrix

60
Q

What uses appositional?

A

Bone and cartilage

61
Q

Interstitial growth

A

Matrix made in a matrix

62
Q

What uses interstitial?

A

Cartilage

63
Q

What % of cartilage and bone is organic?

A

25

64
Q

What makes up the inorganic part of bone?

A

Collagen 1
GAG
Water

65
Q

What makes up the inorganic part of cartilage?

A

Collagen 2

GAG

66
Q

Does cartilage have vessels?

A

No

Year 1 Summative 1 (56 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions