BMS02-1048 Electrochemical Equilibria Flashcards

1
Q

Which 2 forces act on ions?

A

Concentration gradient and electrical gradient, sometimes there are balanced so the con pushing K out is the same as the force pulling K in

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2
Q

How can the equilibrium potential be found?

A

From the Nernst equation if the conc grad value is known

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3
Q

Nernst equation

A

E = RT/zF x ln (Conc out/Conc in)

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4
Q

E

A

Equilibrium potential for the ion

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5
Q

R

A

Universal gas constant

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6
Q

Z

A

Valency (charge) on ion

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7
Q

F

A

Faradays constant

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8
Q

What is the concentration gradient?

A

Store of potential energy to perform osmotic work

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9
Q

How to calculate the gradient?

A

Conc out/Conc in

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10
Q

What does osmotic potential depend on?

A

Number particles in solution and their kinetic energy

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11
Q

Osmotic work is stored as…

A

Potential energy by the concentration gradient

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12
Q

Osmotic work=

A

RT x ln (Conc out/Conc in)

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13
Q

Voltage is…

A

Measure of the work done in separating the ions

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14
Q

What is the unit of charge?

A

Coulomb

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15
Q

Electrical potential difference between 2 points is…

A

Work that must be done to move one coulomb of charge from one point to another

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16
Q

Voltage =

A

Joule / Charge

17
Q

What is potential energy of charge?

A

1 volt when 1 joule of work is done moving 1 coulomb between 2 points

18
Q

What are the units of electrical and osmotic work?

A

Joules/mole

19
Q

Z =

A

Valency

20
Q

How to calculate how many coulombs of charge 1 mole of ion can carry?

A

Valency x Faradays constant

21
Q

Electrical work=

A

Potential difference (E) x Valency (z) x F

22
Q

How is the Nernst equation written for monovalent ions?

A

E = 58 x log (Conc out/Conc in)

23
Q

What are the units for RxT/zxF?

A

Joules per coulomb so its expressed in volts

24
Q

Patch clamping

A

Electrode sealed to cell surface

25
Q

What is used to record voltage?

A

Fluid filled glass capillary tube microelectrode

26
Q

Compare inside and outside recordings

A

Same shape but the outside is less of a strong wave