SA Repro Flashcards
what are the clinical signs of pseudopregnancy?
2 mammary glands swollen.
Nest making, lactation, aggression.
How is pseudopregnancy treated?
Most require no Tx.
Can give galastop: (cabergoline) 5ug/kg SID PO.
Why do permanent pseudopregnancies occur?
spay 25d post-ovulation - prolactin high!
SPAY IN ANOESTRUS
What is the pathogenesis for canine pyometra?
P4 induced endometrial hyperplasia –> pyometra
What is the causative agent for 80% of cases of canine pyometra?
E coli
What is the Tx of choice for pyometra?
Surgery
Outline the medical Tx of pyometra.
ABs 4w after cure
IVFT
PGs - closprostenol EOD or lutalyse TID
Cabergoline SID 2w
Over what value of progesterone is a bitch likely to get pregnant?
> 6ng/ml
Which licenced hormone can be given post-mating to induce abortion?
Oestrogens - 3/5/7d
Aglepristone - x2, 24h apart in 1st 45d.
Which unlicenced hormone can be given post-mating to induce abortion?
Prostaglandins: BID for 5d
Cabergoline: SID
What can be given to the queen to induce abortion?
Oestrogen 1-2d post-mating
Cabergoline + cloprostenol: 30-40d post-mating for best results.
What are the 2 most common causes for failed breeding?
- Mistiming
2. Male infertility
What motility, grade and normal morphology % would be considered excellent in terms of semen quality?
Motility >85%
Normal >80%
Grade 4-5
What motility, grade and normal morphology % would be considered poor in terms of semen quality?
Motility <70%
Normal <70%
Grade 1-2
How are ovarian cysts diagnosed in the bitch?
P4 >2ng/mg for 9-10w
How are ovarian cysts treated in the dog?
Sx removal
What are the 2 causes of short IOI in the bitch?
Ovarian Hyperstimulation (follicular cyst/GCT) Premature fall in P4
What is a follicular cyst?
Thin walled structure.
>1cm
Contains serous fluid
How are follicular cysts treated?
Surgical aspiration
Ovariectomy
GnRH +hCG
What are the signs of follicular cysts in the bitch?
Persistent Oestrus
High persistent oestrogen levels
What is produced by granulosa cell tumorus?
Mostly oestrogens
can produce P4
How do Algepristone and cabergoline cause shorter IOIs?
Decrease P4 levels
Which 2 protozoal infections cause abortion in the bitch?
Toxoplasma Gondii
Neospora Caninum
Which 2 viruses commonly cause abortion in the bitch?
CHV and CDV
What are 2 advantages in terms of fertility, with AI vs natural service of the bitch?
Higher Welping Ratio
High Avg litter size
How long is gestation in the bitch?
58-70d
Which species specific bacteria may cause abortion in the bitch?
Brucella Canis
Which gestational endrocrinopathy is caused by inc GH release?
Gestational Diabetes
GH insulin antagonist - chronic hyperglycaemia leads to abortion
What is the cause of pregnancy hypoglycaemia in the bitch?
Poor nutrition in late gestation
How long does 1st stage labour last in the bitch?
36h if maiden/nervous
6-12 in other dogs
How long does 2nd stage labour last in the bitch?
3-12h
DON’T LET IT EXCEED 12H
What length of time occurs between births of littermates?
5-120m
How long does 3rd stage labour last in the bitch?
15m after each delivery
Greenish discharge normal for 3w
How is uterine inertia in the bitch treated?
10% Ca gluconate
10m
Oxytocin IV
Repeat q30m if necessary.
Which type of bacteria often cause acute metritis and where does it originate?
Gram -ve ascending infection
How is acute metritis treated?
IV fluids, ABs, oxytocin.
Which dogs are predisposed to eclampsia?
Small breeds with large litters
What are the clinical signs of eclampsia and when do they first appear?
Restlessness/pant/pace
Stiffness > spasm > seizures
within 21d of parturition
How is eclampsia treated?
IV Ca and supplements throughout lactation
What commonly causes agalactia and how is it treated?
2e (failure to eject)
Metaclopramide and domperidone
What should be given in severe cases of acute mastitis?
Galastop
How is galactostasis treated and which 2 glands are commonly affected?
Caudal 2 glands - massage and apply cold compress
How can you encourage a bitch to accept her pups?
Put placenta on pups
ACP to calm bitch
How should the bitch be fed post-whelping?
In whelping box
What 2 cell types predominate on vaginal cytology of a bitch in oestrus?
Large intermediate
Cornified
What 2 cell types predominate on vaginal cytology of a bitch in anoestrus/metostrus?
Parabasal
Small intermediate
Which stage of the oestrus cycle is a vaginal cytology foamy?
Metoestrus
Which stage of the oestrus cycle does vaginal cytology contain a significant absence of bacteria and WBCs?
Oestrus
In vaginal cytology, which stage of the oestrus cycle would you find the most WBCs?
Metoestrus
What are the features of vaginal cytology in pro-oestrus?
Parabasal cells
S and L intermediates
Some WBC and RBCs
Bacteria Present
If measuring P4, when should a bitch be mated?
Rise in P4 >4ng/ml - mate in 1 and 3 days.
How is CHV spread?
Direct Contact: oronasal, venereal, transplacental
What is the effect of CHV on neonates <3w old?
Acute, fatal Dz:
V+/D+
Haemorrhage
What is the effect of CHV on adult dogs?
Carrier status
Some repro problems
What is the difficulty of PCR identification for CHV?
False negatives during latency
When are herpesvirus vaccinations given to the dog?
1: Heat/7-10d post-mating
2: 6w later
Booster: at each pregnancy w/same schedule