Clinical GI (SA) Flashcards
Describe acute enteritis.
Profuse large volume diarrhoea.
Describe acute colitis.
Frequent small volume diarrhoea
Haematochezia comes from bleeding where?
Colon
Name 3 causes of acute colitis.
Dietary indiscretion
Whipworm
Protozoa
Which 2 snap test can be performed on canine faeces?
Giardia
Parvovirus
What is the most important factor when treating enteritis?
HYDRATION
How should a non-vomiting/severely dehydrated animal be given fluids?
ORT:
Glucose-electrolyte solution
Apart from maintaining hydration, what else must be done to aid acute enteritis?
restrict food intake 12-24h.
Reintroduce bland diet.
How does maropitant work as an anti-emetic?
NK-1 receptor antagonist
If vomiting persists, a gastric mucosal protectant should be given. Name 3.
Cimetidine (H2 antagonist)
Sucralfate
Antacids
How does kaolin-pectin act as an anti-diarrhoeal?
Binds toxins and excess water to protect mucosa.
How do opioids act as an anti-diarrhoeal?
Slow gut transit
What are the 3 indications for ABs in GE?
Haemorrhagic D+
D+ and pyrexia
Known infection
Which antiemetic is given to dogs?
Apomorphine
Which antiemetic is given to cats?
xylazine
What may be seen on haematology of a dog with HGE?
marked elevation of PCV (60-80)
What is the 1e Tx for HGE in dogs?
IV balanced electrolytes @ 80ml/kg/hr.
Stop when CRT normal and PCV <50
What is regurgitation?
Passive process where undigested food covered by mucus and saliva exit the mouth
What is the gold standard way to assess oesophageal function?
Barium oesophagram + fluoroscopy.
What Dz does the 2M antibody test for?
Masticatory Muscle Myositis
What are 3 causes of 2e megaoesophagus?
MG
Oesophagitis
Hiatal hernia
How is idiopathic megaoesophagus treated?
Postural Feeding
Guarded Px - aspiration pneumonia
What are the 4 main causes of canine oesophagitis?
Ingestion of irritant
FB
Acute/persistent vomiting
Gastric reflux
How should the feeding regime be changed in cases of oesophagitis?
frequent small feeds
What medicines can be given to ease oesophagitis?
Sucralfate
Antacids
Metoclopramide
What are the 3 categories of oesophageal obstruction?
Intraluminal
Intramural
Extramural
Which AB can lead to oesophageal stricture formation in cats?
doxycycline
What method of stricture dilatation has the lowest risk of perforation?
Balloon Dilatation
Bougienage can cause longitudinal shear tears.
What kind of imaging is best for visualisation of oesophageal FB?
PLAIN Rx.
DON’T give barium.
What should be given to a dog after surgical FB removal?
PEG tube
Omeprazole
Sucralfate
Define Pseudoptyalism
Failure to swallow correct volume of saliva
Define Megaoesophagus
Oesophageal dilation w/functional paralysis
What is the cause of an oesophageal stricture?
Fibrosis following ulceration of the mucosa
Which medication can be given locally to ease stricture tightness?
Triamcinolone Acetonide
Where is the most common site of oesophageal FB in the dog?
Lower oesophageal sphincter.
How are oesophageal FB diagnosed?
Rx - NO contrast!
Intermittent chronic V+, with early morning V+ w/bile, poor appetite and gastric bleeding are signs of which Dz? Tx?
Chronic Gastritis
Diet w/novel protein & multiple small meals.
H2 antagonist/PPI
Ranitidine/Metaclopramide also useful.
POSS C/S but not always.
Which congenital deformity in brachycephalic dogs causes vomiting 8h after eating?
Pyloric Stenosis
How is pyloric stenosis diagnosed? Tx?
Barium swallow + Rx
Metaclopramide - prokinetic
OR
Ranitidine (Ach inhibitor) - stimulates empyting and dec acid output
OR
Low dose Erythromycin (stimulate motilin receptors)
A dog presenting in prayer position w/haematemesis, malaena, weight loss, and pain, could have which gastric issue?
Gastric ulcers
Which 2 drugs predispose dogs to peptic ulcers?
NSAIDs
Corticosteroids
Which licenced H2 receptor antagonist is used to Tx gastric ulcers?
Cimetidine
Which PPI is used to Tx gastric ulcers?
Omeprazole
What is the most common gastric neoplasia in:
a) dogs?
b) Cats?
A) Adenocarcinoma
B) Lymphoma
What signs would lead you to suspect gastric adenocarcinoma?
Old Age Chronic V+ WL/Anorexia Haematemesis Anaemia Ptyalism
Which condition may cause haematochezia without tenesmus, mucous or D+?
Rectal Polyps
What should be done before performing canine colonoscopy?
Starve 48h
Polyethylene Glycol 3x 4h apart
2x warm water enemas
Which 2 therapies are used exclusively for LI D+ c/f SI D+?
Fibre Supplement
Sulfasalazine
What are the 3 methods for Dx of tritrichomonas fetus in the cat?
Saline Smear
Culture
PCR
What test is used to measure malabsorption?
Folate/Cobalamin
Which test is used for hypoadrenocorticism?
ACTH stim test / Basal cortisol
Which test is used for hyperthyroidism?
Total Thyroxine
Which test is used for Exocrine pancreatic insufficiency?
TLI
Which test is used for pancreatitis?
PLI
Which neurological disease may lead to constipation? Tx?
Idiopathic Megacolon
Surgery
How is constipation managed?
Laxatives
Enemas
Dietary Management - high fibre
Which 3 feline medical conditions are associated with pancreatitis?
Cholangitis
IBD
Hepatic Lipidosis
DM
Besides the non-specific malaise shown with pancreatitis, what may affected cats/dogs do which is indicative of this Dz?
Prayer Position
What changes are seen to a normal haem/biochem panel in pancreatitis?
Inc WBCC, Glucose, Liver enzymes, bilirubin
Dec Ca
What is needed for a definitive diagnosis of pancreatitis?
Pancreatic biopsy
What is the best Tx for pancreatitis?
SUPPORT: Analgesia (not NSAID), anti-emetics (maropitant), IVFT, antibiosis.
Feed AS SOON AS vomiting stops - via tube if necessary
What is the most common cause of EPI in dogs?
Pancreatic acinar atrophy
What is the most common cause of EPI in cats?
Chronic Pancreatitis
What faceal changes are noted with EPI?
Large volume, foul smelling, loose, greasy faeces.
What changes are noted to appetite with EPI?
Polyphagia
+ coprophagia and pica
What would the TLI value be for a dog with EPI?
<2.5ug/L
What would the TLI value be for a dog with NO EPI?
> 5ug/L
How is EPI Treated?
Pancreatic Enzyme
Low Fibre Diet
Cobalamin supplement
What are single, and multiple PSS’s caused by?
Single - Congenital
Multiple - Acquired (cirrhosis/hypertension)
What is the cause of hepatic encephalopathy?
Dec urea formation from NH3 causes inc blood NH3 & altered CNS fct
What are 4 factors which worsen Hepatic Encephalopathy?
High Protein Diet
GI bleed
Dehydration
Acid Base imbalance
What are 3 hepatic causes of haemorrhage?
Defective prod/storage of clotting factors
Vit K malabsorption
Portal hypertension
What is the most common liver abnormality in dogs?
Reactive hepatopathy
What are 2 bacterial, 3 viral and 1 protozoal, causes of inflammatory hepatopathy?
B: Lepto and bactrial cholangiohepatitis
V: Canine Hepatitis virus, Canine herpes virus, FIP(dry)
P: Toxoplasma
How is paracetamol toxicityin cats treated?
N acyetylcystine
Vitamin C
Support: IVFT, ABs, Charcoal
What are the 5 major DDx for feline icterus?
Cholangitis Complex Dry FIP Lymphoma Lipidosis Pancreatitis
What are the 2 hepatocellular markers in the DOG?
ALT
AST
What are the 2 cholestatic markers in the DOG?
ALP
GGT
Decreases of what may indicate hepatopathy?
Albumin and glucose
Increases of what may indicate hepatopathy?
ALT/ALP
Bile Acids
Bilirubin
Clotting time
What must be done before performing a liver biopsy?
Clotting Profile!!
When is percutaneous liver biopsy CI’ed?
Small Liver
Focal Dz
Extrahepatic Cholestasis
Bleeding disorder/anaemia
Which hepatopathy occurs in young GSDs and Rottweilers, occluding the central vein?
Juvenile Hepatic Fibrosis
What may be seen on biochem with a hepatic portal hypoplasia?
Inc Bile Acids
What are the 2 subtypes of feline cholangitis complex?
Suppurative Cholangitis
Lymphocytic Cholangitis
How should the diet be modified in Chronic Active Hepatits?
Low Cu high Zn
Vit supplement ADEK
Hepatic Diet + cottage cheese (no protein restrictions)
Taurine (Cat)
Which 2 antibiotics are useful for minimising ammonia production in hepatic encephalopathy?
Metronidazole
Ampicillin
In which 2 hepatopathies should glucocorticoids be part of the Tx protocol?
Chronic Active Hepatitis
Hepatic Fibrosis
What are the advantages of using glucocorticoids in hepatopathies?
Stimulates appetite
Anti-inflammatory
Immunosuppressive
Anti-fibrotic
What are the disadvantages of using glucocorticoids in hepatopathies?
Steroid Hepatopathy
Infection risk inc
Fluid Retention
Catabolic
What are the 2 approaches to Tx of Cu hepatopathy in the dog?
Chelate: D-penicillamine/222-tetramine
Block Abs: Oral Zn 1h pre-feeding
How does S-Adenylmethionine aid in hepatopathy?
Aids detoxification and hepatic metabolism.
May aid in toxicities and chemotherapy.
How may milk thistle be helpful for liver Dz?
Free Radical Scavenger
Inhibits Inflm
How can we treat ascites in dogs with liver Dz?
Low Na Diet
Diuresis