Farm Clinical Repro Flashcards
How long is a normal bovine oestrus cycle?
18-24d
How long does uterine involution and regeneration of the endometrium take?
3-4w
What happens in all cows 2w pp?
inc in FSH - 1st follicular wave stimulated
when is the 1st PP oestrus in dairy cows?
2-3w PP
when is the 1st PP oestrus in beef suckles cows?
3w-3m
When does ovulation occur?
24h after signs of oestrus
What hormonal affect do uterine infections have?
Suppress GnRH and pituitary LH secretion
What are the main pathogens responsible for metritis/endometritis?
E coli
T pyogenes
D nodosus
F necrophorum
Define Metritis
Enlarged uterus, purulent uterine discharge detectable
in the vagina.
Within 21d of parturition
What are the 3 grades of metritis?
1: enlarged uterus w/purulent disch. Systemically well.
2: Systemically unwell. (dec milk yield, >39.5, dec DMI)
3. Toxaemic (cold extremities, dull)
Define Pyometra.
Purulent material in uterine lumen
CL present
Closed Cervix
How is Pyometra treated?
PGF
Define Endometritis.
purulent uterine discharge detectable
in the vagina >21d pp
what are the 4 grades of endometritis?
0= clear 1 = flecks of white 2 = <50ml, <50% white 3 = >50ml, lots of white or bloody material
How is clinical endometritis treated?
____
What are cystic follicles?
Fluid filled structure >2.5cm
Ovulates in 10d
No luteal tissue present
What are follicular cysts?
Thin <3mm wall
Fluid filled
Internal diameter >25mm
Last >10d
What do follicular cysts secrete for the 1st half of their lifespan?
Oestradiol (inhibits LH surge)
What are luteal cysts?
Thick wall >3mm
>25mm internal diameter
Fluid filled lacuna
Duration >10d
define bovine abortion.
Calving <270d in gestation
Which notifiable pathogen is a serious abortive agent?
Brucellosis
How do 2e abortive pathogens cause luteolysis and abortion?
Inflammation and PG release
What are 3 main 2e pathogens?
Listeria Monocytogenes
Leptospira borgpetersenii
Salmonella dublin
What are the 2 routes of infection for abortive agents?
Resident repro flora
Transplacental
Haematogenous
Which foetal lesions are associated with transplacental BoHV-1 infection?
Fetal lung (peri-bronchiolar mononuclear inflm & vasculitis)
Fetal liver (centilovular necrosis)
Which pathogen causes placentitis without inflammation, and a pale non-autolysed liver?
BVDv (+ group B strep)
Which pathogen causes foetal bronchopneumonia after crossing the placenta?
T pyogenes
How can we tell when BVDv infection occured in the calf in placenta?
Radio-opaque lines on Tibia
Which pathogen causes IBR?
BHV-1
What is the most commonly diagnosed cause of abortion in the cow?
Neospora
How is neospora diagnosed?
Maternal serology - inc Ab levels!
Test calf at birth
Can also perform brain histopath on dead foetus
What is the incubation period for BDV?
5-7d
When after initial infection are BVD Abs present?
14-21d
What are the 2 biotypes of BVD?
Non-cytopathic: acute Dz. crosses FoetMat barrier –> abortion.
Cytopathic: mucosal Dz in PI animals
How can you test for BVD PI calves?
Ab neg, Ag pos
What is the danger of BVD in PI calves?
Conversion of non-cytopathic biotype to cytopathic.
Also don’t do well as Imm Supp.
Infection with BVD at what age causes congenital abnormalities? (cerebellar hypoplasia etc)
120-285d of gestation
how does cytopathic BVD present?
Ulcerated mucosa
Ill thrift
Diarrhoea
Resp Dz
When can you test calves blood for being PI for BVD?
> 30d
What is the bulk tank PCR detection limit?
1 in 300
where do leptospires survive in the environment?
Water!
Which repro issues are caused by acute lepto cases?
Abortion
Stillbirth
Weak Calf
RFM
How is lepto diagnosed?
Bulk milk - herd level
Identify in aborted tissue
Can do serology
Which 2 antibiotics can be used to treat bovine lepto?
dihydrostreptomycin (25mg /kg sid) or
oxytetracycline (10mg/kg sid)
What are the 3 sources of salmonella?
Faeces
Feed
Fomites
Which is the most common salmonella serovar associated with abortion?
S dublin
When do salmonella infections peak?
Sep to Dec