FARM ID (Cows, Sheep) Flashcards
Which 2 major bovine repsiratory pathogens are paramyxoviruses?
BRSV PI3
How do paramyxoviruses infect cells?
Fusion Proteins fuse viral envelope to cell membrane. Viral Nucelocaspids enter cytoplasm.
Which bovine respiratory pathogen causes interstitial pneumonia and emphysema?
BRSV
Which bovine respiratory pathogen causes bronchitis, bronchiolitis and alveolar thickening?
PI3
Which bovine respiratory pathogen causes intracytoplasmic inclusion bodies in the lungs?
PI3
Which bovine respiratory pathogen causes eosinophilic inclusion bodies in the lungs?
BRSV
Which bovine respiratory pathogen causes disease in cattle 6-18m old?
IBR
Which bovine respiratory virus causes necrosis, predisposing to “shipping fever”?
IBR
Which bovine respiratory pathogen causes IBR?
BHV-1
Which bovine respiratory pathogen destroys alveolar macrophages and lymphoid tissue?
BVDV
Describe what occurs if a cow is infected with BVDV in its 1st trimester.
Abortion
Describe what occurs if a cow is infected with BVDV in its 2nd trimester.
PI calf produced & ?teratogenic effects
Describe what occurs if a cow is infected with BVDV in its 3rd trimester.
Foetus Fights off virus
Bovine respiratory disease complex is a product of which four viruses?
BRSV PI3 BHV BVDV
What is OPA?
Retrovirus –> causes pulmonary adenocarcinoma
What is Maedi?
Retrovirus –> progressive smooth muscle hyperplasia in lungs
Which bovine pathogen causes cuffing pneumonia, septic arthritis, otitis media and mastitis?
Mycoplasma Bovis
Which pathogen targets the cranioventral lung lobes, and is referred to as enzootic pneumonia?
Mycoplasma Bovis (also M haemolytica and pasturella)
Which two bacteria are responsible for shipping fever in cattle?
M haemolytica Pasturella Multocida
What is the characteristic pathology of shipping fever?
Fibrinous pleurisy
Which bacteria is commensal in the UGT but pathogenic in the respiratory tract of cattle?
Histophilus Somnii
Which 2 bacteria are responsible for pasturellosis in sheep?
M. Haemolytica Bibersteinia trehalosi
How is Maedi-visna tested for in sheep?
ELISA
How do we test for BRDC?
ELISA or PCR
What is special about the myocplasma vaccine for cattle?
Autogenous not commercial
Which virus causes enteritis is calves and winter dysentry in cows?
Coronavirus
What are the two major diarrhoeal viruses of cattle?
Rotavirus and Coronavirus
Which coccidial disease causes a zoonotic diarrhoea of calves/lambs?
Cryptosporidium Parvum
Which gram -ve pathogen may cause calf diarrhoea?
E coli
Which pathogen causes acute, fatal diarrhoea in calves <5d old?
ETEC
Which zoonotic pathogen poses no Dz risk to animals, but a large one to humans.
E coli 0157 (VTEC)
What are your main ddx for diarrhoea in a cald >6d old?
Rota/corona/crypto
What type of diarrhoea is caused by ETEC and cholera?
Hypersecretion
What type of diarrhoea is caused by viruses/crypto?
Malabsorptive
how do we treat calf diarrhoea?
IVFT - NOT ABs!
What is the major route of infection for Johnes?
Faeco-Oral
For each clincial case of Johnes, how many animals on the farm are infected?
10-25
At what age do cattle tend to present with clinical signs of johnes?
>3yo
What is the impact of subclinical johnes disease?
Lower Yield Inc lameness Inc mastitis
How long does MAP survive in the environemnt?
12m water 2y soil
Where does MAP survive in the body?
Macrophages
What is the underlying pathology of Johnes?
Granulomata in ileum and LNs Diffuse thickening of gut wall.
Which immune response is protective against MAP?
Th1 response - CMI!
What is the gold standard test for MAP?
Faecal culture
What is the use of ELISA for MAP?
Can detect infectious as detects Ab. Poor for detecting infected. Sens only 30-40%
What are the clinical signs of Johnes?
Bright and alert Weight loss Profuse Diarrhoea Bottle Jaw
At what time point is most of Johnes transmitted?
80% in 1st 4w of life
How can we control Johnes?
Traffic light system Snatch Calving No pooled/waste milk Pen cleaning Purchase history!
What is the danger of the MAP vaccine to TB testing?
Increases chance of false neg - reduced sensitivity
Name the 5 contagious mastitis pathogens
Staph Aureus Strep Uberis Strep Dysgalactiae Strep Agalactiae Coag negative Staph Mycoplasma
Name the 3 environmental mastitis pathogens
Strep Uberis E coli Klebsiella Pneumonia
What is the best way to diagnose common mastitis pathogens?
PCR
Describe the staining/morphology of S aureus.
Gram + cocci
What is the most common mastitis pathogen?
Staph Aureus
What are the 3 ways staph aureus is spread?
Milking Parlous Heifer Teat sucking Flies
why is staph aureus mastitis hard to diagnose?
intermittent shed, survives intracellularly
Which pathogen may cause gangrenous mastitis, or blockage of secretory ducts and abscessation?
Staph aureus