Wilm's Tumour

Question 1

What is a Wilm’s tumour and what is its peak age off presentation?

Answer 1

1. Nephroblastoma - embryonal tumour of the kidney

2. 1 to 3 years of age

Question 2

What are the clinical features of a Wilm’s tumour?

Answer 2

1. Asymptomatic abdominal mass
2. Abdominal distension
3. Haematuria, fever, and hypertension

Question 3

How is a Wilm’s tumour diagnosed?

Answer 3

1. Any child with an abdominal mass - USS
2. CT/MRI to further stage the disease
3. Transcutaneous histological biopsy for diagnosis

Question 4

What is the management for a Wilm’s tumour?

Answer 4

1. Nephrectomy 1st line 4 unilateral tumours followed by chemotherapy
2. Bilateral - chemotherapy then excision of masses to preserve function

Question 5

What is the prognosis of a Wilm’s tumour?

Answer 5

85% 5-year survival