Hypothyroidism Flashcards
1
Q
What is the cause of congenital hypothyroidism?
A
- Agenesis or dysgenesis of the thyroid gland (75%)
2. Maternal thionamide use
2
Q
How is congenital hypothyroidism diagnosed?
A
- Most at asymptomatic stage via newborn screening (detect TSH)
- Does not detect central congenital hypothyroidism (low/unpredictable TSH)
3
Q
What is this a presentation of?
Good/quiet as they sleep for long periods, decreased activity, poor feeding, constipation, hypotonia, large posterior fontanelle, prolonged jaundice.
A
Congenital hypothyroidism
4
Q
What is the management of hypothyroidism?
A
Lifelong thyroxine
5
Q
What are the causes of acquired hypothyrodism?
A
- Hashimoto’s thyroiditis
- Prematurity
- Hypopituitarism
- Down’s syndrome
6
Q
What is this a presentation of?
Slow growth, short stature, delayed puberty, declining school performance.
A
Acquired hypothyroidism
7
Q
How is acquired hypothyroidism diagnosed?
A
Low T4/T3, high TSH.
