Kawasaki Disease

Question 1

What is this describing?
Autoimmune disease resulting in a medium-sized vessel vasculitis. Typically affects children younger than 5-years old, with a peak incidence at 10 months of age.

Answer 1

Kawasaki disease

Question 2

What is this a presentation of?
High-grade fever lasting more than 5 days, resistance to antipyretics. Strawberry tongue, bright red cracked lips. Bilateral conjunctival infection. Red hands and feet which later peel. Diffuse rash. Cervical lymphadenopathy.

Answer 2

Kawasaki disease

Question 3

What is the main complication of Kawasaki disease?

Answer 3

Coronary artery aneurysm development can lead to myocardial infarction and arrhythmias.

Question 4

How is Kawasaki disease diagnosed?

Answer 4

1. Clinically
2. Raised CRP and ESR
3. Echocardiograph

Question 5

The management for Kawasaki disease?

Answer 5

1. Aim is to prevent coronary artery aneurysms, IV Igs.

2. High dose aspirin despite the risk of Reye’s syndrome.