CKD Flashcards

1
Q

What is the definition of CKD?

A

eGFR <60 in the absence of any other kidney abnormalities or <90 if there is a known structural defect or abnormality on urinalysis.

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2
Q

What age group has a lower physiological GFR?

A

<2 years old

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3
Q

What are the causes of CKD in childhood?

A
  1. congenital hypoplastic or dysplastic kidneys
  2. reflux nephropathy
  3. obstructive uropathy
  4. focal segmental glomerulonephritis
  5. PKD
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4
Q

What are the clinical features of CKD?

A
  1. asymptomatic in early stages
  2. as it advances - lethargy, anorexia, nausea and vomiting
  3. hypertension, poor growth, anaemia, hyperphosphatemia, hypocalcaemia
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5
Q

What is the management for CKD in children?

A
  1. Manage complications
  2. dialysis or renal transplant
  3. ensure adequate nutrition
  4. supplements, EPO, iron, folic acid, vitamin D
  5. recombinant SC growth hormone
  6. ACEi
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