Pharmocology

Question 1

Acid-controlling medications: PPIs (omeprazole)
and H2
blockers (famotidine)

Answer 1

are taken daily
to suppress acid production, while antacids
neutralize acid and are used as needed for quick
symptom relief.

Question 2

PPIs: Long-term PPI use (omeprazole,
pantoprazole)

Answer 2

increases risk of C. difficile
infection and bone fractures due to reduced
stomach acid.

Question 3

Antacids:

Answer 3

Take antacids ≥1 hour apart from other medications to prevent decreased absorption of
other drugs.

Question 4

Sucralfate:

Answer 4

Sucralfate forms a temporary
protective barrier over gastric ulcers and should be
taken 1 hour before meals and at bedtime. Separate from other medications: Take other
medications at least 2 hr before sucralfate to prevent absorption issues.

Question 5

Misoprostol:

Answer 5

Misoprostol is contraindicated
in pregnancy because it causes uterine
contractions and can lead to miscarriage.

Question 6

H2
Receptor
Blockers
cimetidine
famotidine

Answer 6

Taken daily for long-
term symptom
management
Cimetidine inhibits liver
enzymes: increases toxicity risk
of warfarin, phenytoin,
and theophylline

Question 7

Antacids
calcium carbonate
aluminum hydroxide
magnesium hydroxide

Answer 7

Taken as needed to
neutralize gastric acid
Separate from other
medications by ≥1 hr.
Use cautiously in
clients with HTN and
HF (some antacids
contain high sodium).