pcos management Flashcards

1
Q

What criteria are used to diagnose Polycystic Ovarian Syndrome (PCOS) according to the Rotterdam Criteria?

A

PCOS is diagnosed using the Rotterdam Criteria which includes at least 2 of the following: Oligo/anovulation (> 2 years), clinical or biochemical features of hyperandrogenism, polycystic ovaries on ultrasound (> 12 in one/both ovaries measuring 2-9 mm or ovarian volume > 10cm3).

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2
Q

What is the first-line treatment for menstrual issues in women with PCOS who are not planning pregnancy?

A

Lifestyle advice, including weight reduction and dietary modification, is the first-line treatment for menstrual issues in women with PCOS who are not planning pregnancy.

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3
Q

What are the screening recommendations for women with PCOS regarding diabetes and cardiovascular disease?

A

Women with PCOS should be screened for Type 2 Diabetes (OGTT) and cardiovascular disease.

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4
Q

What medications can be used to manage amenorrhea or dysfunctional uterine bleeding in women with PCOS?

A

COCP, cyclical oral progesterone, or LNG-IUS can be used to manage amenorrhea or dysfunctional uterine bleeding in women with PCOS.

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5
Q

What is the mechanism by which COCP helps relieve androgenic symptoms in PCOS?

A

COCP increases sex hormone-binding globulin, which helps relieve androgenic symptoms in PCOS.

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6
Q

What are the options for women with PCOS who have too many risk factors for COCP?

A

Women with PCOS who have too many risk factors for COCP can take 3-monthly progesterone to induce withdrawal bleed, ensuring it occurs at least every 3-4 months to protect the endometrium.

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7
Q

What treatments are available for hirsutism and androgenic symptoms in PCOS?

A

Treatments for hirsutism and androgenic symptoms in PCOS include topical eflornithine cream, co-cyprindiol (dianette), cyproterone acetate, metformin, GnRH analogues, and surgical treatment (laser or electrolysis).

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8
Q

What is the first-line treatment for subfertility in women with PCOS who are planning pregnancy and have a normal BMI?

A

Clomiphene is the first-line treatment for subfertility in women with PCOS who are planning pregnancy and have a normal BMI.

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9
Q

What are the risks associated with clomiphene use for ovulation induction in PCOS?

A

Clomiphene use for ovulation induction in PCOS carries an increased risk of multiple pregnancies.

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10
Q

What procedure may be considered for women with PCOS to prompt ovulatory cycles?

A

Laparoscopic ovarian drilling (LOD) may be considered for women with PCOS to prompt ovulatory cycles.

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11
Q

What are the risk factors for PCOS?

A

Risk factors for PCOS include family history and obesity.

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12
Q

How should the diagnosis of PCOS be explained to patients?

A

PCOS is a condition with no clear cause that leads to abnormalities in hormone levels, resulting in the symptoms experienced.

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13
Q

What are the main consequences of PCOS?

A

The main consequences of PCOS include irregular periods, subfertility, metabolic syndrome (sugar dysregulation, easier to gain weight), cardiovascular disease, and acne.

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14
Q

What management strategies should be recommended for women with PCOS who are concerned about fertility?

A

For women with PCOS concerned about fertility, recommend weight loss, clomiphene +/- metformin, and consider laparoscopic ovarian drilling (LOD).

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15
Q

What management strategies should be recommended for women with PCOS who are concerned about irregular periods?

A

For women with PCOS concerned about irregular periods, recommend COCP or progestogens, aiming for at least 3-4 bleeds per year.

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16
Q

What metabolic syndrome-related conditions should be checked in women with PCOS?

A

Women with PCOS should be checked for diabetes, high cholesterol, and heart disease as part of managing metabolic syndrome-related conditions.

17
Q

Which specialists should be included in the multidisciplinary team (MDT) for managing PCOS?

A

The multidisciplinary team (MDT) for managing PCOS should include dieticians, gynecologists, and endocrinologists.