flashcards_pcos
What are the Rotterdam Criteria for diagnosing PCOS?
Oligo/anovulation (> 2 years), clinical or biochemical features of hyperandrogenism, polycystic ovaries on ultrasound.
What is the first-line treatment for managing menstrual issues in PCOS before or when not planning pregnancy?
Lifestyle advice including weight reduction and dietary modification.
What are the options for managing amenorrhoea or dysfunctional uterine bleeding in PCOS?
COCP, cyclical oral progesterone, or LNG-IUS.
What treatments are available for hirsutism/androgenic symptoms in PCOS?
Topical eflornithine cream, co-cyprindiol (dianette), cyproterone acetate, metformin, GnRH analogues, surgical treatment (laser or electrolysis).
What is the first-line treatment for subfertility in PCOS when planning pregnancy?
Clomiphene, usually added with metformin after 3 failed cycles.
What procedure can be used to treat subfertility in PCOS?
Laparoscopic ovarian drilling.
What are the risk factors for PCOS?
Family history, obesity.
How common is PCOS in the UK?
1 in 10 women in the UK.
What are the main consequences of PCOS?
Irregular periods, subfertility, metabolic syndrome (sugar dysregulation, easier to gain weight), cardiovascular disease, acne.
How should the management of PCOS be tailored to a patient’s biggest concern?
Fertility: recommend weight loss, clomiphene +/- metformin, consider LOD. Periods: COCP or progestogens (aiming for at least 3-4 bleeds per year). Metabolic Syndrome: check for DM, high cholesterol, heart disease (manage accordingly).
