ALPHA FETO PROTEIN Flashcards
What is alpha-fetoprotein (AFP)?
Alpha-fetoprotein (AFP) is a protein produced by the developing fetus.
What conditions are associated with increased AFP levels?
Conditions associated with increased AFP levels include neural tube defects, abdominal wall defects, and multiple pregnancy.
What conditions are associated with decreased AFP levels?
Conditions associated with decreased AFP levels include Down’s syndrome, trisomy 18, and maternal diabetes mellitus.
Which neural tube defects are linked to increased AFP?
Neural tube defects linked to increased AFP include meningocele, myelomeningocele, and anencephaly.
Which abdominal wall defects are linked to increased AFP?
Abdominal wall defects linked to increased AFP include omphalocele and gastroschisis.
What chromosomal abnormalities are linked to decreased AFP?
Chromosomal abnormalities linked to decreased AFP include Down’s syndrome and trisomy 18.
What maternal condition is associated with decreased AFP?
Maternal diabetes mellitus is associated with decreased AFP levels.
What is a common cause of increased AFP related to pregnancy?
A common cause of increased AFP related to pregnancy is multiple pregnancy.