GESTATIONAL THROMBOCYTOPENIA VS ITP Flashcards
What is gestational thrombocytopenia?
Gestational thrombocytopenia is a relatively common condition of pregnancy resulting from a combination of dilution, decreased production, and increased destruction of platelets.
What causes gestational thrombocytopenia?
Gestational thrombocytopenia is caused by increased work of the maternal spleen leading to mild sequestration.
What is immune thrombocytopenia (ITP)?
Immune thrombocytopenia (ITP) is an autoimmune condition usually associated with acute purpuric episodes in children but may present as a chronic relapsing course in women.
How is ITP usually presented in children?
ITP in children is usually presented with acute purpuric episodes.
How does ITP typically present in women?
ITP typically presents as a chronic relapsing course in women.
What is a key factor in differentiating between ITP and gestational thrombocytopenia?
Differentiating between ITP and gestational thrombocytopenia often relies on a careful history.
What may indicate gestational thrombocytopenia as pregnancy progresses?
Gestational thrombocytopenia may be considered more likely if the platelet count continues to fall as pregnancy progresses, although this is not a reliable sign.
How is a dangerously thrombocytopenic pregnant patient usually treated?
A dangerously thrombocytopenic pregnant patient is usually treated with steroids, and a diagnosis of ITP is assumed.
What tests may be needed for pregnant women with low platelets or a history of ITP?
Pregnant women with low platelets during a booking visit or those with a previous diagnosis of ITP may need to be tested for serum antiplatelet antibodies.
How does gestational thrombocytopenia affect the neonate?
Gestational thrombocytopenia does not affect the neonate.
How can ITP affect the neonate?
ITP can affect the neonate if maternal antibodies cross the placenta.
What treatment might be indicated for a newborn with thrombocytopenia due to maternal ITP?
Platelet transfusions might be indicated for a newborn with thrombocytopenia due to maternal ITP.
What can be done to determine if there is an inherited thrombocytopenia in the newborn?
Serial platelet counts can be performed to determine if there is an inherited thrombocytopenia in the newborn.
