4.4.4 Toxicology (Drug that Requires TDM) Flashcards
Digoxin
a. Analgesics
b. Cardioactive drugs
c. Antiepileptics/Antisezure
d. Psychoactive drugs/Antidepressants
b
Acetylsalicylate (Aspirin)
a. Analgesics
b. Cardioactive drugs
c. Antiepileptics/Antisezure
d. Psychoactive drugs/Antidepressants
a
Acetaminophen (Tyenol)
a. Analgesics
b. Cardioactive drugs
c. Antiepileptics/Antisezure
d. Psychoactive drugs/Antidepressants
a
Antiarrhythmics
a. Analgesics
b. Cardioactive drugs
c. Antiepileptics/Antisezure
d. Psychoactive drugs/Antidepressants
b
Analgesic:
used as an analgesic, antipyretic, and anti-inflammatory;
exhibits ANTIPLATELET activity through inhibition of cyclooxygenase
a. Acetylsalicylate (Aspirin)
b. Acetaminophen (Tyenol)
a
Analgesic:
Used in patient with bleeding disorder
a. Acetylsalicylate (Aspirin)
b. Acetaminophen (Tyenol)
b
Analgesic:
toxic effect includes hepatotoxicity (damage of the liver)
a. Acetylsalicylate (Aspirin)
b. Acetaminophen (Tyenol)
b
Analgesic:
toxic effects include mixed acid-base disorder, and Reye Syndrome
a. Acetylsalicylate (Aspirin)
b. Acetaminophen (Tyenol)
a
Cardioactive drugs/Cardiotropic:
a cardiac glycoside used to treat congestive heart failure
a. Digoxin
b. Antiarryhtmics
a
Cardioactive drugs/Cardiotropic:
used to treat tachyarrhythmia
a. Digoxin
b. Antiarryhtmics
b
Cardioactive drugs/Cardiotropic:
Calcium blocker
a. Class I
b. Class II
c. Class III
d. Class IV
d
Cardioactive drugs/Cardiotropic:
Sodium channel blocker
a. Class I
b. Class II
c. Class III
d. Class IV
a
Cardioactive drugs/Cardiotropic:
Beta-blocker/beta-a adrenergic receptor blocker
a. Class I
b. Class II
c. Class III
d. Class IV
b
Cardioactive drugs/Cardiotropic:
Potassium channel blocker
a. Class I
b. Class II
c. Class III
d. Class IV
c
Cardioactive drugs/Cardiotropic:
Lidocaine,
Quinidine,
Disopyramide,
Procainamide
a. Class I
b. Class II
c. Class III
d. Class IV
a
Cardioactive drugs/Cardiotropic:
Propanolol
a. Class I
b. Class II
c. Class III
d. Class IV
b
Cardioactive drugs/Cardiotropic:
Verapamil
a. Class I
b. Class II
c. Class III
d. Class IV
d
Cardioactive drugs/Cardiotropic:
Amiodarone
a. Class I
b. Class II
c. Class III
d. Class IV
c
Psychoactive drugs/Antidepressants:
Phenobarbital
a. First Gen anticonvulsants
b. New Gen anticonvulsants
a
Psychoactive drugs/Antidepressants:
Tiagabine
a. First Gen anticonvulsants
b. New Gen anticonvulsants
b
Psychoactive drugs/Antidepressants:
Vigabatrin
a. First Gen anticonvulsants
b. New Gen anticonvulsants
b
Psychoactive drugs/Antidepressants:
Gabapentin
a. First Gen anticonvulsants
b. New Gen anticonvulsants
b
Psychoactive drugs/Antidepressants:
Benzodiazepines
a. First Gen anticonvulsants
b. New Gen anticonvulsants
a
Psychoactive drugs/Antidepressants:
Phenytoin (Dilantin)
a. First Gen anticonvulsants
b. New Gen anticonvulsants
a
Psychoactive drugs/Antidepressants:
Carbamazepine (Tergetol)
a. First Gen anticonvulsants
b. New Gen anticonvulsants
a
Psychoactive drugs/Antidepressants:
Topiramate
a. First Gen anticonvulsants
b. New Gen anticonvulsants
b
Psychoactive drugs/Antidepressants:
Felbamate
a. First Gen anticonvulsants
b. New Gen anticonvulsants
b
Psychoactive drugs/Antidepressants:
(1st Gen)
Used to treat grand mal / tonic-clonic seizures
a. Phenobarbital
b. Benzodiazepines
c. Phenytoin
d. Carbamazepine
a, b, c, d
Psychoactive drugs/Antidepressants:
(1st Gen)
slow-acting barbiturate; inactive form primidone
a. Phenobarbital
b. Benzodiazepines
c. Phenytoin
d. Carbamazepine
a
Psychoactive drugs/Antidepressants:
(1st Gen)
GABAergic
a. Phenobarbital
b. Benzodiazepines
c. Phenytoin
d. Carbamazepine
a, b
Psychoactive drugs/Antidepressants:
(1st Gen)
Glutamatergic
a. Phenobarbital
b. Benzodiazepines
c. Phenytoin
d. Carbamazepine
c, d
Psychoactive drugs/Antidepressants:
(1st Gen)
Glutamatergic
a. Ethosuximide
b. Valproic acid (Depakote)
a
Psychoactive drugs/Antidepressants:
(1st Gen)
Used to treat PETIT mal / absence
seizures
a. Ethosuximide
b. Valproic acid (Depakote)
a, b
Neuroleptics
a. Analgesics
b. Cardioactive drugs
c. Antiepileptics/Antisezure
d. Psychoactive drugs/Antidepressants
d
Antimanic and Antidepressants
a. Analgesics
b. Cardioactive drugs
c. Antiepileptics/Antisezure
d. Psychoactive drugs/Antidepressants
d
Psychoactive drugs/Antidepressants
antipsychotic major tranquilizers used to treat schizophrenia
a. Neuroleptics
b. Antimanic agents
c. Antidepressants
a
Psychoactive drugs/Antidepressants
Uses lithium to treat bipolar or manic-depressive disorder
a. Neuroleptics
b. Antimanic agents
c. Antidepressants
b
Psychoactive drugs/Antidepressants
Use to treat clinical depression
a. Neuroleptics
b. Antimanic agents
c. Antidepressants
c
Aminoglycosides
a. Bronchodilators
b. Antibiotics
c. Immunosuppressants
d. Antineoplastics
b
Glycopeptides
a. Bronchodilators
b. Antibiotics
c. Immunosuppressants
d. Antineoplastics
b
Caffeine
a. Bronchodilators
b. Antibiotics
c. Immunosuppressants
d. Antineoplastics
a
Theophylline
a. Bronchodilators
b. Antibiotics
c. Immunosuppressants
d. Antineoplastics
a
Bronchodilators:
Used for treatment of neonatal apnea
a. Theophylline
b. Caffeine
b
Bronchodilators:
Used for treatment of asthma and other COPDs
a. Theophylline
b. Caffeine
a
Antibiotics:
Used to treat gram-negative infections, carries a toxic nature that causes nephrotoxicity and cytotoxicity
a. Aminoglycosides
b. Glycopeptides
a
Antibiotics:
Vancomycin
a. Aminoglycosides
b. Glycopeptides
b
Antibiotics:
used to treat gram positive infections and is associated with red man syndrome
a. Aminoglycosides
b. Glycopeptides
d
Methotrexate
a. Bronchodilators
b. Antibiotics
c. Immunosuppressants
d. Antineoplastics
d
Busulfan
a. Bronchodilators
b. Antibiotics
c. Immunosuppressants
d. Antineoplastics
d
Calcineurin inhibitor
a. Bronchodilators
b. Antibiotics
c. Immunosuppressants
d. Antineoplastics
c
Prevets graft rejection / Graft vs host
a. Bronchodilators
b. Antibiotics
c. Immunosuppressants
d. Antineoplastics
c
Immunosuppressant:
- Cyclosporine
- Tacrolimus
a. Calcineurin inhibitor
b. Prolifertion signal inhibitors
a
Immunosuppressant:
- Sirolimus
- Everolimus
- Mycophenolate
a. Calcineurin inhibitor
b. Prolifertion signal inhibitors
b
Antineoplastics:
Requires the administration of Leucovorin to spare the normal cells from its effects
a. Methotrexate
b. Busulfan
a
Antineoplastics:
Used to treat leukemia and lymphomas
a. Methotrexate
b. Busulfan
b
