3.2.6 Clinical Enzymology (Miscellaneous Enzymes) Flashcards
Alcoholic liver disease, Microsomal induction of drugs and alcohol
a. Gamma glutamyl transferase
b. 5 Nucleotidase
c. Acid Phosphatase
d. Aldolase
a
Uses Szasz method
a. Gamma glutamyl transferase
b. 5 Nucleotidase
c. Acid Phosphatase
d. Aldolase
a
Best alcoholic marker
a. Gamma glutamyl transferase
b. 5 Nucleotidase
c. Acid Phosphatase
d. Aldolase
e. ALP
a
If ALP is high, Increase in GGT, and 5NT
a. Liver
b. Bone
a
If ALP is high, Normal in GGT, and 5NT
a. Liver
b. Bone
b
Intrahepatic cholestasis Only
a. Gamma glutamyl transferase
b. 5 Nucleotidase
c. Acid Phosphatase
d. Aldolase
b
GGP and ALP has Extrahepatic cholestasis
The following can be used to identify the source of increase ALP:
- GGP
- 5 NT
- ACE
Which of the following does not belong?
ACE
GGP, ALP, and 5NT are increased in HBD
T or F
T
Szasz method:
p-nitroaniline is a product that produces what color?
a. Red
b. Yellow
c. Blue
b
A major source of Acid phosphatase?
a. Prostate
b. RBC
c. Heart
a and b
A major source and richest source of Acid phosphatase?
a. Prostate
b. RBC
c. Heart
a
Specimen consideration of Acid phosphatase is
Avoid hemolysis
T or F
T
Prostatic CA / Hyperplasia
a. Gamma glutamyl transferase
b. 5 Nucleotidase
c. Acid Phosphatase
d. Aldolase
c
Not practically use today
Resolution of Rape cases
a. Gamma glutamyl transferase
b. 5 Nucleotidase
c. Acid Phosphatase
d. Aldolase
c
Roy method
a. Gamma glutamyl transferase
b. 5 Nucleotidase
c. Acid Phosphatase
d. Aldolase
c
Roy method includes substrate which is:
a. Alanine
b. Pyruvate
c. Thymolphtalein monophosphate
c
Chemical inhibition for ACP includes:
- Tartrait
- Copper
- Formaldehyde
T or F
T
Inhibits prostatic ACP
a. Tartrait
b. Copper
c. Formaldehyde
a
Inhibits RBC ACP
a. Tartrait
b. Copper
c. Formaldehyde
b and c
Elevation in Skeletal muscle
a. Gamma glutamyl transferase
b. 5 Nucleotidase
c. Acid Phosphatase
d. Aldolase
d
Elevated Hepatic disorders
a. Glutamate dehydrogenase
b. Glutathione-S-transferase
c. ACE
d. Glycogen phosphorylase
e. Trypsin
a and b
Include MHD
What leukemia is associated with tartrait resistance ACP?
Hairy cell Leukemia
Increase in Blood pressure regulation
a. Glutamate dehydrogenase
b. Glutathione-S-transferase
c. ACE
d. Glycogen phosphorylase
e. Trypsin
c
Elevate in Myocardial infarction
a. Glutamate dehydrogenase
b. Glutathione-S-transferase
c. ACE
d. Glycogen phosphorylase
e. Trypsin
d
Elevated in Acute pancreatitis
a. Glutamate dehydrogenase
b. Glutathione-S-transferase
c. ACE
d. Glycogen phosphorylase
e. Trypsin
e
Clinically significant when it is disease
a. Chymotrypsin
b. G-6-PD
c. Pyruvate kinase
d. Pseudocholinesterase
all
Chronic pancreatic deficiency
a. Chymotrypsin
b. G-6-PD
c. Pyruvate kinase
d. Pseudocholinesterase
a
Pesticide poisoning
a. Chymotrypsin
b. G-6-PD
c. Pyruvate kinase
d. Pseudocholinesterase
d
Drug-induced Hemolytic anemia
a. Chymotrypsin
b. G-6-PD
c. Pyruvate kinase
d. Pseudocholinesterase
b
Hemolytic disorder
a. Chymotrypsin
b. G-6-PD
c. Pyruvate kinase
d. Pseudocholinesterase
c
Liver disease and Genetic variance (Abnormal response to muscle relaxant)
a. Chymotrypsin
b. G-6-PD
c. Pyruvate kinase
d. Pseudocholinesterase
d
Clinically significant when decrease RBC
a. Chymotrypsin
b. G-6-PD
c. Pyruvate kinase
d. Pseudocholinesterase
b and c
Clinically significant when decrease in serum
a. Chymotrypsin
b. G-6-PD
c. Pyruvate kinase
d. Pseudocholinesterase
d
