2.2.4 Lipids and Lipoproteins (Fredrickson Classification of Hyperlipoproteinemias)

Question 1

Particle:

CM

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 1

a and f

Question 2

Particle:

CM, VLDL

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 2

f

Question 3

Particle:

VLDL

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 3

c, d, e, f

Question 4

Particle:

VLDL, LDL

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 4

c

Question 5

Particle:

VLDL ONLY

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 5

e

Question 6

Particle:

LDL

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 6

b, c

Question 7

Particle:

LDL ONLY

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 7

b

Question 8

Particle:

IDL, Beta-VLDL

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 8

d

Question 9

Representative Disorders:

Familial hypercholesterolemia

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 9

b

Question 10

Representative Disorders:

Familial dysbetalipoproteinemia

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 10

d

Question 11

Representative Disorders:

Primary hypertriglyceridemia

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 11

e

Question 12

Representative Disorders:

Mixed hyperlipidemia

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 12

f

Question 13

Representative Disorders:

Familial chylomicronemia or LPL deficiency

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 13

a

Question 14

Representative Disorders:

Familial combined hyperlipoproteinemia

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 14

c

Question 15

Clinical Presentation:

Eruptive Xanthomas, Acute pancreatitis, Low cardiac risk

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 15

a

Question 16

Clinical Presentation:

Xanthelasma, Premature CHD, High Cardiac Risk

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 16

b

Question 17

Clinical Presentation:

Isolated Xanthelasma, Premature coronary heart disease, high Cardiac risk

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 17

c

Question 18

Clinical Presentation:

Eruptive Xanthoma, Premature CHD, high Cardiac Risk

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 18

d

Question 19

Clinical Presentation:

Eruptive Xanthoma, may be associated with Premature CHD, Low Cardiac Risk

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 19

e and f

Question 20

Findings:

High TG, may have normal or High TC

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 20

e and f

Question 21

Findings:

High TG Only

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 21

a

Question 22

Findings:

High LDL and TC

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 22

b

Question 23

Findings:

High LDL, TC, and TG

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 23

c

Question 24

Findings:

High TG, and TC

a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5

Answer 24

d

Question 25

↑ CM and/or VLDL:
-↑ Triglycerides = ↑ risk for pancreatitis, eruptive xanthomas

↑ LDL and/or IDL:
-↑ Total Cholesterol = ↑ cardiac risk, Xanthelasma

T or F

Answer 25

T