2.2.4 Lipids and Lipoproteins (Fredrickson Classification of Hyperlipoproteinemias) Flashcards
Particle:
CM
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
a and f
Particle:
CM, VLDL
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
f
Particle:
VLDL
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
c, d, e, f
Particle:
VLDL, LDL
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
c
Particle:
VLDL ONLY
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
e
Particle:
LDL
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
b, c
Particle:
LDL ONLY
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
b
Particle:
IDL, Beta-VLDL
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
d
Representative Disorders:
Familial hypercholesterolemia
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
b
Representative Disorders:
Familial dysbetalipoproteinemia
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
d
Representative Disorders:
Primary hypertriglyceridemia
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
e
Representative Disorders:
Mixed hyperlipidemia
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
f
Representative Disorders:
Familial chylomicronemia or LPL deficiency
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
a
Representative Disorders:
Familial combined hyperlipoproteinemia
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
c
Clinical Presentation:
Eruptive Xanthomas, Acute pancreatitis, Low cardiac risk
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
a
Clinical Presentation:
Xanthelasma, Premature CHD, High Cardiac Risk
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
b
Clinical Presentation:
Isolated Xanthelasma, Premature coronary heart disease, high Cardiac risk
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
c
Clinical Presentation:
Eruptive Xanthoma, Premature CHD, high Cardiac Risk
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
d
Clinical Presentation:
Eruptive Xanthoma, may be associated with Premature CHD, Low Cardiac Risk
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
e and f
Findings:
High TG, may have normal or High TC
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
e and f
Findings:
High TG Only
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
a
Findings:
High LDL and TC
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
b
Findings:
High LDL, TC, and TG
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
c
Findings:
High TG, and TC
a. Type 1
b. Type 2a
c. Type 2b
d. Type 3
e. Type 4
f. Type 5
d
↑ CM and/or VLDL:
-↑ Triglycerides = ↑ risk for pancreatitis, eruptive xanthomas
↑ LDL and/or IDL:
-↑ Total Cholesterol = ↑ cardiac risk, Xanthelasma
T or F
T
