2.2.2 Lipids and Lipoproteins (Major classes of lipoproteins)) Flashcards
Density:
<0.93
a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL
a
Density:
0.93-1.006
a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL
b
Density:
1.006-1.019
a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL
e
Density:
1.019-1.063
a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL
c
Density:
1.062 - 1.21
a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL
d
Electrophoretic mobility:
Pre-beta
a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL
b
Electrophoretic mobility:
Alpha
a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL
d
Electrophoretic mobility:
Beta
a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL
c
Electrophoretic mobility:
origin
a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL
a
Major Component:
Cholesterol
a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL
c
Major Component:
Protein 50%
a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL
d
Major Component:
Tryglyerides (Endogenous
a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL
b
Major Component:
Triglycerides (Exogenous)
a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL
a
Apolipoproteins:
B48, C, E
a. Chylomicron
b. VLDL
c. LDL
d. HDL
a
Apolipoproteins:
B100, C, E
a. Chylomicron
b. VLDL
c. LDL
d. HDL
b
Apolipoproteins:
B100
a. Chylomicron
b. VLDL
c. LDL
d. HDL
c
Apolipoproteins:
AI, AII, C, E
a. Chylomicron
b. VLDL
c. LDL
d. HDL
d
Comments:
Transports endogenous triglycerides
a. Chylomicron
b. VLDL
c. LDL
d. HDL
b
Comments:
Transports Exogenous triglycerides
a. Chylomicron
b. VLDL
c. LDL
d. HDL
a
Comments:
Transports cholesterol to peripheral tissues
a. Chylomicron
b. VLDL
c. LDL
d. HDL
c
Comments:
Facilitates reverse cholesterol transports (From th tissues back to the liver)
a. Chylomicron
b. VLDL
c. LDL
d. HDL
d
Gold standard for lipoprotein analysis?
Ultracentrifugation / Density gradient centrifugation
2 important methods for lipoprotein analysis?
Ultracentrifugation and electrophoresis
Chylomicron has lower density than the water
T or F
T
IDL is considered Major lipoprotein
T or F
F
Minor
Arrangement of lipoproteins from least dense to most dense?
Chylomicrons>VLDL>LDL>HDL
Lipoproteins travels from Cathode (-) to Anode (+)
T or F
T
Arrangement of lipoproteins in terms of mobility in electrophoresis from CATHODE (-) TO ANODE (+):
Chylomicrons>LDL>VLDL>HDL
The most Triglyceride rich
a. Chylomicron
b. VLDL
c. LDL
d. HDL
a
The triglyceride transported by chylomicrons is dietary (Exogenous)
T or F
T
The triglyceride carried by VLDL is synthesized by the ?
Liver
Main determinant of cholesterol level?
LDL
Known as atherogenic or may promote atherosclerosis
LDL
most protein-rich lipoprotein
HDL
A lipoprotein that serves as a scavenger that can remove
cholesterol excess deposits.
HDL
HDL deliver Cholesterol back to the liver so it can be use to synthesize ?
Bile
Important in the saponification of digestion of dietary lipids in the intestine.
Bile
chylomicrons are not taken up by the liver because of its huge size
T or F
T
Chylomicrons needs to be hydrolyze into remnants so it can be taken up by the liver
T or F
T
Enzyme catalyze the hydrolysis of chylomicrons, IDL, and VLDL
a. Protein Lipase
b. Lipoprotein lipase
c. Lipidolipase
d. Lipase
b
Liver synthesizes the chylomicrons remnants into?
VLDL
VLDL is hydrlyzes into smaller particle which is?
IDL
IDL is also hydrolyzes in to much smaller particle which is?
LDL
This can be easily taken up by the cell
LDL is a metabolite of VLDL
T or F
T
Function of cholesterol in the body includes:
- Synthesis of Steroid hormone
- Synthesis of Vit D
- Synthesis of Bile
Which of the following does not belong?
None
Why does VLDL migrate faster in electrophoresis?
It has higher magnitude of NEGATIVE charge
What is the major lipid component (Excluding the protein) of the HDL?
a. Triglyceride
b. Phospholipids
c. Fatty acids
Phopholipids
