4.2.3.1 Major Hormones (Thyroid Gland) Flashcards

1
Q

A butterfly-shaped organ consisting of two lobes (right and left) that rest on
each side of the trachea, bridged by a band of tissue called________

a. Isthmus
b. Thyroid
c. Colloid
d. Thyroglobulin

A

a

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2
Q

In thyroid gland, each lobe consist of?

A

Follicles

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3
Q

Follicles are spheres of thyroid cells surrounding a core of viscous substance termed?

a. Isthmus
b. Thyroid
c. Colloid
d. Thyroglobulin

A

c

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4
Q

The colloid, that central core of viscous substance consists mainly of

a. Isthmus
b. Thyroid
c. Colloid
d. Thyroglobulin

A

d

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5
Q

A glycoprotein manufactured exclusively by the thyroid follicular cells which are used for thyroid hormone synthesis

A

Thyroglobulin

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6
Q

Two types of cell in Thyroid:

also known as C-cells. Produces
Calcitonin.

a. Follicular cells
b. Parafollicular cells

A

b

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7
Q

Two types of cell in Thyroid:

encircled in the colloid. Produces T4 & T3

a. Follicular cells
b. Parafollicular cells

A

a

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8
Q

100% of T4 originated from follicular cells while 20% is T3 since ito comes from monodeiodination of T4

T or F

A

T

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9
Q

Thyroid hormones are primarily boound to transport protein

T or F

A

T

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10
Q

70% of T4 are bound to

a. Thyroxine binding globulin (TBG)
b. Thyroxine binding prealbumin (TBPA) / Transthyretin

A

a

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11
Q

20% of T4 are bound to?

a. Thyroxine binding globulin (TBG)
b. Thyroxine binding prealbumin (TBPA) / Transthyretin

A

b

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12
Q

10% of T4 are bound to?

A

Albumin

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13
Q

All thyroid are 100% bound

T or F

A

F

small percentage are not bound

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14
Q

0.04% of ____ and 0.4% ____ are unbound

A

T4

T3

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15
Q

Function is none

a. Thyroxine (T4)
b. 3,5,3’-triiodothyronine (T3)
c. Reverse T3 (3,3’,5’-triiodothyronine)
d. Calcitonin

A

c

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16
Q

Regulation of Calcium level

a. Thyroxine (T4)
b. 3,5,3’-triiodothyronine (T3)
c. Reverse T3 (3,3’,5’-triiodothyronine)
d. Calcitonin

A

d

17
Q

Regulation of O2 consumptions, heat production, growth sexual maturity, metabolism

a. Thyroxine (T4)
b. 3,5,3’-triiodothyronine (T3)
c. Reverse T3 (3,3’,5’-triiodothyronine)
d. Calcitonin

A

a and b

18
Q

Clinical significance:

Medullary thyroid carcinoma

a. Thyroxine (T4)
b. 3,5,3’-triiodothyronine (T3)
c. Reverse T3 (3,3’,5’-triiodothyronine)
d. Calcitonin

A

d

19
Q

Clinical significance:

Non-thyroidal illness/Euthyroid sick syndrome

a. Thyroxine (T4)
b. 3,5,3’-triiodothyronine (T3)
c. Reverse T3 (3,3’,5’-triiodothyronine)
d. Calcitonin

A

c

20
Q

Graves disease, T3 thyrotoxicosis

a. Primary hyperthyroidism
b. Primary hypothyroidism

A

a

21
Q

Hashimoto’s thyroiditis, myxedema, Congenital

a. Primary hyperthyroidism
b. Primary hypothyroidism

A

b