1.2.2 Blood Collection and Specimen Consideration (Categories of Additives) Flashcards
What is the most preferred specimen in Clinical Chemistry?
Serum
If serum cannot be used in CC, what is the alternative for it?
Heparinized plasma
Least interference in CC
a. EDTA
b. Citrate
c. Oxalate
d. Heparin
d
Color of EDTA for CDC
Lavender
Color for EDTA for Crossmatching?
Pink
Color of Citrate for Coagulation?
Light Blue
Color of Citrate for ESR (Erythrocytic sedimentation rate)
Black
Color of Oxalate?
Gray
Color of Heparin
Green
EDTA, Citrate, and Oxalate is not recommended due to? (MOA)
Removal of Calcium
Chelation of Calcium happens which of the following additives:
a. EDTA
b. Citrate
c. Oxalate
d. All of the above
a and b
Precipitation of Calcium happens on which of the additive?
a. EDTA
b. Citrate
c. Oxalate
d. All of the above
c
EDTA, Citrate, and Oxalate causes a False ________ due to:
- Sodium
- Potassium
Increase
These Additive contains Sodium potassium which cause F increase
Which among these additives:EDTA, Citrate, and Oxalate causes false increase in SODIUM?
EDTA (Disodium EDTA)
Which among these additives:EDTA, Citrate, and Oxalate causes false increase in Potassium?
Oxalate (Potassium Oxalate)
EDTA, Citrate, and Oxalate causes a False ________ due to:
- Calcium
Decrease
Due to removal of Calcium
EDTA, Citrate, and Oxalate causes a False ________ due to:
- Mg
- PO4
- Fe
Decrease
Calcium and Magnesium binds to enzymes (Serve as cofactor)
Some of the bind to calcium
MOA of Heparin?
Inhibition of thrombin (Thrombin 3)
Silica and thrombin are known as _____ activators
Clot
Color code for Silica?
Red (Plastic)
Color code for Thrombin?
Orange
Causes Short clotting time
a. Gel separator
b. Silica
c. Thrombin
d. NaF
b and c
Recommended for STAT serum test
a. Gel separator
b. Silica
c. Thrombin
d. NaF
b and c
Color for Gel + silica
Gold or Red/black spot
Color for Gel + heparin
Light green or Green with Gray spots
Which of the following use for SST (Serum separator tube)
a. Red with black spots
b. Light green
c. Green with grey spots
d. Orange
a
Which of the following use for PST (Potassium Sensitivity test)
a. Red with black spots
b. Light green
c. Green with grey spots
d. Orange
b and c
Color for NaF/Iodoacetate
Grey or Light grey
Primarily antiglycolytic agents (MOA)
a. Citrate
b. Oxalate
c. NaF/Iodoacetate
d. Silica
c
Gel is not recommended for ___________ since it absorbs it
a. Drug testing
b. Therapeutic Drug monitoring
c. IV drug test
d.Insertion of Drugs via IV
b
What are the drugs that are absorbed by the Gel?
a. Tricyclic antidepressants
b. Antiarrhythmic
c. None of the above
d. All of the above
d
The drugs that are absorbed by the Gel causes false _________
decrease
NaF inhibits __________
Urease
MOA for NaF/Iodoacetate is inhibition of __________
Enolase
Sodium flouride causes False decrease on what analyte?
BUN
