Signal Transduction Flashcards

1
Q

Topics

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2
Q

Fundamentals of Molecular Medicine

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3
Q

What is Cancer?

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4
Q

Percent Distribution of Cancer

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5
Q

Cancer Death Rates

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6
Q

Cancer Rates/Trends

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7
Q

Cancer Treatment Types

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8
Q

Distribution of Cancer Sites

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9
Q

Erythropoetin and JAK-STAT Transduction

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10
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11
Q
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Erythroid Hyperplasia in Bone Marrow

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12
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13
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14
Q

Normal Cells and Signaling Events

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15
Q

Serum and Cells that are starved from Serum

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16
Q

Cyclohexamide

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17
Q

Immediate Early Proteins and Delayed Early Genes

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18
Q

James Bond Model of Cancer

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19
Q

Oncogenes

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20
Q

Selected Oncogenes and Their Mode of Activation

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21
Q

Oncogenes and RAS

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22
Q

RAS and Cancer

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23
Q

Receptor that Activates RAS

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24
Q

Paracrine Growth Factors

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25
Q

Autocrine Growth Factors

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26
Q

Antibodies and Cancer Therapies

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27
Q

Herceptin

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28
Q

Blood Brain Barrier and Cancer

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29
Q

Steroid Hormones

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30
Q

RAS activation favors…

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31
Q

MYC and Cyclin D

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32
Q

Cyclin D

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33
Q

Retinoblastoma and Cancer

Which Cell Cycle is Effected?

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34
Q

Constitutive Activation

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35
Q

Mode of Activation of Selected Oncogenes

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36
Q

Result of Constitutive Activation

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37
Q

Constitutively Activated Receptors in Cancer

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38
Q

RAS and Point Mutations

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39
Q

RAS Point Mutations And Downstream Kinases

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40
Q

Effects of RAS Activation/Point Mutation

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41
Q

mTOR

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42
Q

Function of mTOR

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43
Q

Rapamycin Derative and Tumors

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44
Q

Complexity of mTOR Interactions

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45
Q

ABL

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46
Q

ABL Translocation

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47
Q

BCR ABL and Gleevec

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48
Q

Polycythemia

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49
Q

Jakafi

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50
Q

Proteosome

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51
Q

Cachexia and Inhibitors of Proteosomes

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52
Q

Velcade

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53
Q

Two Ways to Reduce Cell Cancer Growth

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54
Q

Getting Cancer Treatments into The Body

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