Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Fundamentals of Molecular Medicine > Amino Acid Metabolism Pt. II > Flashcards

Amino Acid Metabolism Pt. II Flashcards

1
Q

Phenylalanine Degredation

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Alcaptonuria

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Phenylketonuria

A

Defect Associated with Phe Metabolism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Tyrosinemia Type I

A

When Fumarylacetoacetate Hydrolase accumulates it gets reduced to Succinylacetoacete (diagnostic) which leads to kidney and liver damage.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Tyrosinemia Type II

A

Treatment of Type II just stops production of homogentisiic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Biopterin Cycle

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Neurotransmitter Structures

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Neurotransmitter Structures Pt. II

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

An OTC Defect may interfere with the synthesis of which neurotransmitter in the brain?

GABA

Acetylcholine

Epinephrine

Serotonin

Glycine

A

GABA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Homocysteinemia/uria Pathway

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Homocysteinemia/uria Features

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Causes of Elevated Homocysteine

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What does Homocysteine Do?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Treatments for Elevated Homocysteine

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which reaction requires both Folate and B12?

Succinate to Succinyl CoA

SAH to Homocysteine

Homocysteine to methionine

Homocysteine to Cystathionine

A

Homocysteine to methionine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Homocysteine and Neural Tube Defects

A
17
Q

What about Vitamin B12

A
18
Q

The use of methylmalonic acid for fatty acid biosynthesis will lead to which one of the following?

Short Chain Fatty Acids

Odd Chain Fatty Acids

Branched Chain Fatty Acids

Very Long Chain Fatty Acids

No Fatty Acids will be Synthesized

A

Branched Chain Fatty Acids

19
Q

B12 and Folate Deficiencies

A
20
Q

Liver and B12 Deficiencies

A
21
Q

The classic finding in someone with b12 deficiency is megaloblastic anemia— large immature blood cells. Why?

Inability to make homocysteine

Inability to Make Succinyl CoA

Inability to make DNA

Inability to Make RNA

A

Inability to make DNA

22
Q

Branch Chain Amino Acids

A
23
Q

Branch Chained Amino Acids Pt. II

A
24
Q

Branch Chained Amino Acids Pt. III

A
25
Q

Branch Chained Amino Acid Metabolism

A
26
Q

Glycine Metabolic Disorders

A
27
Q

Non-Ketotic Hyperglycinemia

A
28
Q

Hyperglycemia may also result from which one of the following?

PKU

B12 Deficiency

Vitamin C Deficiency

B1 Deficeincy

Using an MAO inhibitor

OTC Deficiency

A

B12 Deficiency — Leads to functional folate deficiency and the formation of glycine its conversion to serine requires folate.

29
Q

Biosynthesis of Heme

A
30
Q

Synthesis of Gamma Aminolevulinic Acid

A
31
Q

Lead Poisoning

A
32
Q

Heme Synthesis Pt. II

A
33
Q

Defects in Heme Biosynthesis

A
34
Q

Heme Degredation

A
35
Q

Regulatory Aspects of Amino Acid Degredation

A
36
Q

Role of Alanine in Muscle Amino Acid Degredation

A
37
Q

Amino Acid Flux Between Tissues

A
38
Q
A

Maple Syrup Urine Disease.

Fundamentals of Molecular Medicine (77 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions