Body Fluid Spaces Flashcards
Compartmentalization of Fluids
Compartments:
Plasma
Capillary Membrane
Interstitial Fluid
Cell Membrane
Intracellular Fluid

E. Freezing point depression
It all depends on the number of particles.

D. Elicits no net water flow from the cells.
Intracellular Concentrations of Ions

Intracellular Concentration of Glucose and Proteins

Total mOsm/L in Plasma vs. Interstitial vs. Intracellular

Fluid and Body Weight

Body water content

Extracellular vs. Intracellular Fluid Content

Blood Volume vs. Plasma Volume

Hematocrit

1 - Hct

Whole Blood Volume
1-Hct — should be called the Plasmacrit.

How do you measure a pool?

Fluid Space Measurement Dye-Dilution Technique

Measurement of Body Fluid Spaces

Plasma Markers

Extracellular Fluid Markers

Total Body Water Markers (Z)

Time to Reach Steady State for Each Compartment

Water Flow Accross Biological Membranes

Size and Charge vs. Membrane

Forces of Water movement

Osmotic Pressure

Osmolar Concentration

Effect of a 150 mM solution of NaCl

Effective Osomotic Pressure

Van’t Hoff Equation

Movement of Water accross Capillary

Colloid Osmotic Pressure

Ultrafiltration
filtration using a medium fine enough to retain colloidal particles, viruses, or large molecules.

Filtration Rate/Starling Equation

Interstitium and Starling Equation

Blood Pressure

Concept of Net Filtration

Movement of Water accross Cell Membrane


D. Plasma Space, Interstitial same and intracellular space would all loose fluid proportionally.
When we sweat we lose more water than we do salt. So ECF becomes concentrated and water will flow from inside to outside cell. But all 3 would loose water proportionally.

B. Most of the water would come from the extracellular space (plasma + interstitial) Why is this different? Because when we bleed we lost an isotonic fluid so we didn’t create an osmotic imbalance. Therefore there’s no osmotic force that draws out water from our intracellular space.
Isotonic vs. Isosmotic

Solutions and Isosmotic vs. Isotonic


D. Expansion of both the extracellular space and the intracellular space
Glucose get’s taken into the cells very quickly and you end up with a infusion of water with essentially no solute. This is very bad.
Blood cells will undergo hemolysis — RBC’s would explode because they would take in the water.

