Drug Absorption

Question 1

ADME

Answer 1

Question 2

Routes by Which Solutes can Transverse Membrane

Answer 2

Question 3

Drug Absorption and Distribution

Answer 3

Question 4

Drug Characterisitics that Favor Diffusion

Answer 4

Question 5

Acid

Answer 5

Question 6

Base

Answer 6

Question 7

Weak Acid/Base

Answer 7

Question 8

Weak Acid/Base

Answer 8

Question 9

Common Drug Acid/Base Functional Groups

Answer 9

Question 10

Acids/Bases Vs. Pka’s

Answer 10

Question 11

Examples of Weak Acids and Bases

Answer 11

Question 12

Weak Acid and Permeability

Answer 12

Question 13

Weak Base and Permeability

Answer 13

Question 14

Answer 14

Question 15

Henderson Hasselbach Equation

Answer 15

Question 16

What are the most important determinants of moving accross the membrane?

Answer 16

Question 17

Importance of Hydrophobicity for Drugs with Similar Pka Values

Answer 17

Question 18

Transcapillary Movement

Answer 18

Question 19

Blood Brain Barrier

Answer 19

Question 20

Routes for Drug Administration and Elimination

Answer 20

Question 21

IV vs. First Pass Effect

Answer 21

Question 22

Why is first pass effect a challenge Clinically?

Answer 22

Question 23

Oral Administration Advantages vs. Disadvantages and First pass Metabolism

Answer 23

Question 24

Stomach, Small Intestine, Large Intestine

Answer 24

Question 25

Sub-Buccal/Sub Lingual Absorption and Absorption Rates

Answer 25

Question 26

Paraternal Administration (Lungs)

Answer 26

Question 27

Paraternal Administration (Skin)

Answer 27

Question 28

Intramuscular vs. Subcutaneous

Answer 28

Question 29

Intravenous

Answer 29

Question 30

Epidural

Answer 30

Question 31

Intrathecal

Answer 31

Question 32

Intraperitoneal

Answer 32

Question 33

Routes vs. Time Administration with Cocaine

Answer 33

Question 34

Thiopental a lipid soluble anasthetic

Answer 34

Question 35

Major Determinants of Drug Absorption from the Gut

Answer 35

Question 36

Placental Fetus/Milk/Uncharged Drugs

Answer 36

Question 37

Volume of Distribution

Answer 37

Question 38

Plasma Volume for Different Drugs

Answer 38

Question 39

Low vs. High Vd

Answer 39

Question 40

Drugs that Bind to Albumin

Answer 40

Question 41

Bioavailability

Answer 41

Question 42

Drug Metabolism

Answer 42

Question 43

Two Phases of Drug Metabolism

Answer 43

Question 44

Drugs and Phases

Answer 44

Question 45

Overdose Toxicity and Acetominophen

Answer 45

Question 46

Liver Cytochrome P450

Answer 46

Question 47

Drugs and Age Considerations

Answer 47

Question 48

Pharmacogenetics

Answer 48

Question 49

pH and Resorbtion

Answer 49