Phospholipid and Glycolipid Metabolism Pt. II

Question 1

Ganglioside Function

Answer 1

Question 2

Biosynthesis of GM1

Answer 2

Question 3

Glycosphingolipid Degredation

Answer 3

Question 4

Which one of the following is another example of a lysosomal storage disease

Von Gierke Disease

Cori Disease

MCAD

Refsum

Pompe Disease

Answer 4

Pompe Disease — Build up of glycogen and loss of glucosidase activity in the lysosome.

Question 5

Pathway I to Lactosyl Ceramide

Answer 5

Question 6

Second Pathway to Lactosyl Ceramide

Answer 6

Question 7

Lactosyl Ceramide to Ceramide

Answer 7

Question 8

Second Pathway to Ceramide

Answer 8

Question 9

Third Pathway to Ceramide

Answer 9

Question 10

Common Features of the Sphingolipidoses

Answer 10

Question 11

Generalized Gangliosidoses

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

Answer 11

Question 12

Tay Sach’s Disease

Answer 12

Question 13

Sandhoff’s Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

Answer 13

Question 14

Fabry’s Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

Answer 14

Question 15

Ceramide Lactoside Lipidosis

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

Answer 15

Question 16

Metachromatic Leukodystrophy

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

Answer 16

Question 17

Krabbe’s Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

Answer 17

Question 18

Guacher’s Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

Answer 18

Question 19

Niemann-Pick Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

Answer 19

Question 20

Farber’s Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

Answer 20

Question 21

What disease corresponds to the loss of Sailic Acid?

Answer 21

There is no disease is the loss of saillic acid.

Question 22

Biochemical Basis for TaySach’s Disease

Answer 22

Question 23

Biochemical Properties of Hexosaminidase A

Answer 23

Question 24

Biochemical Properties of Hexosamindase B

Answer 24

Question 25

Sandhoff’s Activator Disease

Answer 25

Question 26

Summary of GM2 Related Diseases

Answer 26

Question 27

Glycerophospholipids

Answer 27

Question 28

Transbilayer Lipid Asymmetry

Answer 28

Question 29

PhosphotidylInositol

Answer 29

Question 30

The PI Cycle

Answer 30

Question 31

Second Messenger Generation

Answer 31

Question 32

Signaling

Answer 32

Question 33

What other protein is activated by a g-protein?

Protein kinase A

Glycogen Phosphorylase kinase

Adneylyl cyclase

Pyruvate Kinase

Glut4 Transporters

Answer 33

Adneylyl cyclase

Question 34

Treatment of phosphatidylinosital bisphosphate with cohopohlipase c will generate which of the following?

PA and Inosital phosphate

DAG and IP3

PA and Inositol Triphosphate (IP3)

PA and Inositol Bisphosphate (IP2)

Answer 34

DAG and IP3

Question 35

The PI Cycle

Answer 35

Question 36

Biologically Active Compounds in the PI Cycle

Answer 36

Question 37

Other Important Lipids

Answer 37

Question 38

Answer 38

IDK? Figure It Out!