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Fundamentals of Molecular Medicine > Phospholipid and Glycolipid Metabolism Pt. II > Flashcards

Phospholipid and Glycolipid Metabolism Pt. II Flashcards

1
Q

Ganglioside Function

A
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2
Q

Biosynthesis of GM1

A
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3
Q

Glycosphingolipid Degredation

A
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4
Q

Which one of the following is another example of a lysosomal storage disease

Von Gierke Disease

Cori Disease

MCAD

Refsum

Pompe Disease

A

Pompe Disease — Build up of glycogen and loss of glucosidase activity in the lysosome.

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5
Q

Pathway I to Lactosyl Ceramide

A
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6
Q

Second Pathway to Lactosyl Ceramide

A
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7
Q

Lactosyl Ceramide to Ceramide

A
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8
Q

Second Pathway to Ceramide

A
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9
Q

Third Pathway to Ceramide

A
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10
Q

Common Features of the Sphingolipidoses

A
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11
Q

Generalized Gangliosidoses

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

A
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12
Q

Tay Sach’s Disease

A
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13
Q

Sandhoff’s Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

A
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14
Q

Fabry’s Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

A
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15
Q

Ceramide Lactoside Lipidosis

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

A
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16
Q

Metachromatic Leukodystrophy

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

A
17
Q

Krabbe’s Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

A
18
Q

Guacher’s Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

A
19
Q

Niemann-Pick Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

A
20
Q

Farber’s Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

A
21
Q

What disease corresponds to the loss of Sailic Acid?

A

There is no disease is the loss of saillic acid.

22
Q

Biochemical Basis for TaySach’s Disease

A
23
Q

Biochemical Properties of Hexosaminidase A

A
24
Q

Biochemical Properties of Hexosamindase B

A
25
Q

Sandhoff’s Activator Disease

A
26
Q

Summary of GM2 Related Diseases

A
27
Q

Glycerophospholipids

A
28
Q

Transbilayer Lipid Asymmetry

A
29
Q

PhosphotidylInositol

A
30
Q

The PI Cycle

A
31
Q

Second Messenger Generation

A
32
Q

Signaling

A
33
Q

What other protein is activated by a g-protein?

Protein kinase A

Glycogen Phosphorylase kinase

Adneylyl cyclase

Pyruvate Kinase

Glut4 Transporters

A

Adneylyl cyclase

34
Q

Treatment of phosphatidylinosital bisphosphate with cohopohlipase c will generate which of the following?

PA and Inosital phosphate

DAG and IP3

PA and Inositol Triphosphate (IP3)

PA and Inositol Bisphosphate (IP2)

A

DAG and IP3

35
Q

The PI Cycle

A
36
Q

Biologically Active Compounds in the PI Cycle

A
37
Q

Other Important Lipids

A
38
Q
A

IDK? Figure It Out!

Fundamentals of Molecular Medicine (77 decks)

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