DNA Replication

Question 1

What is semi-conservative replicaiton?

What is the function of a replication fork?

Answer 1

Question 2

Origins of Replication

Answer 2

Question 3

How does the old replication theory violate semi-conservative replication?

Answer 3

Question 4

Events at the Replication Fork

Answer 4

Question 5

Template strand for the leading strand is always

Answer 5

Is the template strand for leading strand is always 3’ to 5’ going into the fork

Question 6

The template for Lagging strand is always…

Answer 6

The template for Lagging strand is always 5’ to 3’ going into the fork

Question 7

Discontinuous synthesis

Answer 7

Discontinuous synthesis — Okazaki Fragments — Lagging Strand

Question 8

Okazaki Fragments move opposite direction of the…

Answer 8

Leading strand.

Okazaki Fragments move out of the fork!

Question 9

DNA Polymerase I

Answer 9

Question 10

DNA Ligase

Answer 10

Question 11

Inverse Symmetry of Leading and Lagging Strands in Replication fork

Answer 11

Question 12

Forming and growing the bidirectional DNA Replication Bubble

Answer 12

Question 13

Image Type?

Significance?

Answer 13

Question 14

Proof Reading

Answer 14

Question 15

Eukaryotic Replication vs. Prokaryotic Replication

Answer 15

Question 16

How does Replication Deal with the Unwinding Problem?

Answer 16

Question 17

Eukaryotic Chromosomes vs. Prokaryotic Chromosomes

Answer 17

Question 18

Telomeres Lagging Strand Replication Problem

Answer 18

Question 19

Solving the problem of incomplete replication of telomeres

Answer 19

Question 20

Telomerase in Disease, Aging, and Cancer

Answer 20

Question 21

Take Home Points

Answer 21