Fibrous Proteins Flashcards
1
Q
Fibrous Protein
A

2
Q
Collagen
A

3
Q
Collagen and Collagen Related Diseases
A

4
Q
What is the Pathology?

A

5
Q
Pathology?

A

6
Q
Pathology?

A

7
Q
Pathology?

A

8
Q

A

9
Q

A

10
Q
Mutation Underlying Osteogenesis Imperfecta
A

11
Q
Levels of Collagen Structure
A

12
Q
Collagen Role in Bone Formation
A

13
Q
Levels of Collagen Structure Models
A

14
Q
Collagen Primary Structure
A

15
Q
Hydroxyproline
A

16
Q
Collagen Primary Structure and Interchain Hydrogen Bonding
A

17
Q
Model of Tripple Helix
A

18
Q
Stabilizing the Triple Helix
A

19
Q
Roles of Hydroxyproline
A

20
Q
Collagen Synthesis
A

21
Q
Steps in Collagen Biosynthesis
A

22
Q
Function of Collagen Pro-Peptides
A

23
Q
Collagen Pro-Peptides
A

24
Q
Collagen Biosynthesis from transcription to formation
A

25
Hydroxylation of Lysine

26
Hydroxylation of Proline

27
Why is Ascorbate acid essential in Collagen Biosynthesis

28
Role of Hydroxyproline

29
Lysine and Proline Hydroxylases

30
Scurvy

31
Cross-Link Formation in Collagen

32
Post translational modification in lysine crosslink formation

33
One type of Cross-Link Seen in Collagen

34
Collagen Disorders

35
Elastin

36
What is Elastin

37
Major differences between Collagen and Elastin

38
Williams Syndrome and Supravalvular Aortic Stenosis

39


40
Elastin Primary Structure

41
Elastin Biosynthesis from transcription to formation

42
Entropy Driven Elastic Recoil

43
Elastin Open and Closed State

44
Elastin Stretching the Limits

45
Desmosine

46
Building Elastin

47
Fibrillin and Fibulin

48
Fibrillin 1 Secretion

49
Marfan's Syndrome

50


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53
Conclusion
