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Fundamentals of Molecular Medicine > Fibrous Proteins > Flashcards

Fibrous Proteins Flashcards

1
Q

Fibrous Protein

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2
Q

Collagen

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3
Q

Collagen and Collagen Related Diseases

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4
Q

What is the Pathology?

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5
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Pathology?

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6
Q

Pathology?

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7
Q

Pathology?

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8
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9
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10
Q

Mutation Underlying Osteogenesis Imperfecta

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11
Q

Levels of Collagen Structure

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12
Q

Collagen Role in Bone Formation

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13
Q

Levels of Collagen Structure Models

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14
Q

Collagen Primary Structure

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15
Q

Hydroxyproline

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16
Q

Collagen Primary Structure and Interchain Hydrogen Bonding

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17
Q

Model of Tripple Helix

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18
Q

Stabilizing the Triple Helix

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19
Q

Roles of Hydroxyproline

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20
Q

Collagen Synthesis

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21
Q

Steps in Collagen Biosynthesis

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22
Q

Function of Collagen Pro-Peptides

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23
Q

Collagen Pro-Peptides

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24
Q

Collagen Biosynthesis from transcription to formation

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25
Q

Hydroxylation of Lysine

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26
Q

Hydroxylation of Proline

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27
Q

Why is Ascorbate acid essential in Collagen Biosynthesis

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28
Q

Role of Hydroxyproline

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29
Q

Lysine and Proline Hydroxylases

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30
Q

Scurvy

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31
Q

Cross-Link Formation in Collagen

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32
Q

Post translational modification in lysine crosslink formation

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33
Q

One type of Cross-Link Seen in Collagen

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34
Q

Collagen Disorders

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35
Q

Elastin

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36
Q

What is Elastin

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37
Q

Major differences between Collagen and Elastin

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38
Q

Williams Syndrome and Supravalvular Aortic Stenosis

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39
Q
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40
Q

Elastin Primary Structure

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41
Q

Elastin Biosynthesis from transcription to formation

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42
Q

Entropy Driven Elastic Recoil

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43
Q

Elastin Open and Closed State

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44
Q

Elastin Stretching the Limits

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45
Q

Desmosine

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46
Q

Building Elastin

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47
Q

Fibrillin and Fibulin

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48
Q

Fibrillin 1 Secretion

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49
Q

Marfan’s Syndrome

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50
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51
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52
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53
Q

Conclusion

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Fundamentals of Molecular Medicine (77 decks)

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