Fibrous Proteins Flashcards

1
Q

Fibrous Protein

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2
Q

Collagen

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3
Q

Collagen and Collagen Related Diseases

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4
Q

What is the Pathology?

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5
Q

Pathology?

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6
Q

Pathology?

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7
Q

Pathology?

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8
Q
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9
Q
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10
Q

Mutation Underlying Osteogenesis Imperfecta

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11
Q

Levels of Collagen Structure

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12
Q

Collagen Role in Bone Formation

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13
Q

Levels of Collagen Structure Models

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14
Q

Collagen Primary Structure

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15
Q

Hydroxyproline

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16
Q

Collagen Primary Structure and Interchain Hydrogen Bonding

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17
Q

Model of Tripple Helix

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18
Q

Stabilizing the Triple Helix

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19
Q

Roles of Hydroxyproline

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20
Q

Collagen Synthesis

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21
Q

Steps in Collagen Biosynthesis

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22
Q

Function of Collagen Pro-Peptides

23
Q

Collagen Pro-Peptides

24
Q

Collagen Biosynthesis from transcription to formation

25
Hydroxylation of Lysine
26
Hydroxylation of Proline
27
Why is Ascorbate acid essential in Collagen Biosynthesis
28
Role of Hydroxyproline
29
Lysine and Proline Hydroxylases
30
Scurvy
31
Cross-Link Formation in Collagen
32
Post translational modification in lysine crosslink formation
33
One type of Cross-Link Seen in Collagen
34
Collagen Disorders
35
Elastin
36
What is Elastin
37
Major differences between Collagen and Elastin
38
Williams Syndrome and Supravalvular Aortic Stenosis
39
40
Elastin Primary Structure
41
Elastin Biosynthesis from transcription to formation
42
Entropy Driven Elastic Recoil
43
Elastin Open and Closed State
44
Elastin Stretching the Limits
45
Desmosine
46
Building Elastin
47
Fibrillin and Fibulin
48
Fibrillin 1 Secretion
49
Marfan's Syndrome
50
51
52
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Conclusion