Innate Immunity Flashcards by Omar Saqr

Q

What ab’s activate complement?

A

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Q

Effector Functions of Complement

A

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Q

Physiological Activities of Complement

A

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Q

Opsonization by C3B

A

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Q

Immune Adherence vs. Opsonization

A

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Q

What mechanism protects against tetanus Toxin?

A

Neutralization

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Q

What is the major role of complement?

A

Major Role of Complement is actually inflammation not the lysis aspect

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Q

Anaphylatoxins

A

activate mast cells to release histamines

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Q

What is the most powerful attractant for Neutrophils?

A

C5a is the most powerful attractant for neutrophils

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Q

What is an important aspect of F-Met in bacteria?

A

F-Met is another attractant

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Q

What is the role of Anaphylatoxins?

A

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Q

3 Major Roles of Complement

A

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Q

C3 Convertase

A

Common to both Alternate and Classical Pathway of Complement?

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Q

Describe the function of C3 Convertase

A

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Q

How is C5 Convertase made and what is it’s function?

A

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Q

What opsonins are part of the MAC Complex?

A

Q

Overview of Formation of MAC

A

Q

Roles of C5-C9

Don’t memorize just Read.

A

Q

Desribe the overall pathway that is common to complement

A

Q

1st Step of the Classical Pathway

A

Q

2nd Step of the Classical Pathway

A

Q

Complement Fixation

A

Q

Describe the Steps of the Alternate Pathway

A

Q

Stabilization of Alternate C3 Convertase

A

Q

Properdin

A

Q

Overview of All 3 Pathways

A

Q

Comparision of All 3 Pathways

A

Q

C1 Esterase Inhibitor

and

Decay Accelerating Factor

A

Q

Deficiencies in Classical Pathway

A

Q

DAF Deficiency

C3 Deficiency

and C5-C8 Deficiency

A

Q

Peroxysmal Nocturnal Hemoglobinuria

A

Q

Table of Complement Proteins and Effects of their Deficiency

A

Q

Overview of Complement showing where DAF and C1Esterase deficiencies are

A

Q

Answer the Following Questions

A

Q

True or False

A