Humoral Immunity Flashcards

1
Q

Effector Functions of Ig Classes

A

Most Abundant = IgG = workhorseIgD and IgE are rarest.

Immunity to fetus — IgG

IgM always expressed first

IgG expressed during memory response Mucosa is IgA

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2
Q

[Antibody] vs. Time After Immunization

A
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3
Q

IgM vs. IgG after First Exposure

A
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4
Q
A

IgG

Opsonization = IgG

Complement = IgM and IgG

Hypersensitivity = IgE FC Receptors = Mass Cells and Basophils express them

IgD

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5
Q
A

IgA = Respiratory tract

Anaphylaxis = IgE

IgG Convalescent patient

IgA is Breast feeding

Complement = IgG

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6
Q

Process of Opsonization?

Ig Class?

A
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7
Q

What Ig are involved in Opsonization?

A
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8
Q
A
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9
Q
A
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10
Q
A
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11
Q

Fraction of Adult Level of Serum Immunoglobulins

A
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12
Q

Affinity of IgM vs. IgG

A
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13
Q

Physiological Roles of Ag-Ab Interaction

A
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14
Q

Neutralization

A
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15
Q

FC Receptors

A
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16
Q

IgE Role in Allergies

A
17
Q

Immediate Hypersensitivity

A
18
Q

Antibody Isotype and Effector Functions

A
19
Q

Affinity vs. Avidity

A
20
Q

IgM vs. IgG Affinity vs. Avidity

A
21
Q

Ag-Ab Complex Formation

A
22
Q

Antibody Titer

A
23
Q

What is the Antibody Titer?

A

This is a titer for 1:512

24
Q

Elisa

A

Elisa Assay. You’re looking for antibody against organisms.

You coat the well with HIV protein.

Add Test Antiserum

25
Q

Western Blot

A
26
Q

Isohemagluttinins

A
27
Q

Blood Typing

A
28
Q

Rh Disease

A
29
Q
A
30
Q
A

Coombs Test

Indirect Coombs Test

31
Q

Direct vs. Indirect Coombs Test

A
32
Q
A
33
Q

Coombs Reagent

and

RhoGAM

A
34
Q
A

Isohemagglutinins are IgM class which doesn’t cross the placental barrier so you don’t have those types of problems.