Humoral Immunity Flashcards by Omar Saqr

Q

Effector Functions of Ig Classes

A

Most Abundant = IgG = workhorseIgD and IgE are rarest.

Immunity to fetus — IgG

IgM always expressed first

IgG expressed during memory response Mucosa is IgA

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Q

[Antibody] vs. Time After Immunization

A

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Q

IgM vs. IgG after First Exposure

A

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Q

A

IgG

Opsonization = IgG

Complement = IgM and IgG

Hypersensitivity = IgE FC Receptors = Mass Cells and Basophils express them

IgD

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Q

A

IgA = Respiratory tract

Anaphylaxis = IgE

IgG Convalescent patient

IgA is Breast feeding

Complement = IgG

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Q

Process of Opsonization?

Ig Class?

A

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Q

What Ig are involved in Opsonization?

A

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A

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A

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Q

Fraction of Adult Level of Serum Immunoglobulins

A

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Q

Affinity of IgM vs. IgG

A

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Q

Physiological Roles of Ag-Ab Interaction

A

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Q

Neutralization

A

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Q

FC Receptors

A

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Q

IgE Role in Allergies

A

Q

Immediate Hypersensitivity

A

Q

Antibody Isotype and Effector Functions

A

Q

Affinity vs. Avidity

A

Q

IgM vs. IgG Affinity vs. Avidity

A

Q

Ag-Ab Complex Formation

A

Q

Antibody Titer

A

Q

What is the Antibody Titer?

A

This is a titer for 1:512

Q

Elisa

A

Elisa Assay. You’re looking for antibody against organisms.

You coat the well with HIV protein.

Add Test Antiserum

Q

Western Blot

A

Q

Isohemagluttinins

A

Q

Blood Typing

A

Q

Rh Disease

A

Q

A

Q

A

Coombs Test

Indirect Coombs Test

Q

Direct vs. Indirect Coombs Test

A

Q

A

Q

Coombs Reagent

and

RhoGAM

A

Q

A

Isohemagglutinins are IgM class which doesn’t cross the placental barrier so you don’t have those types of problems.