Pharmacokinetics Pt. I Flashcards

1
Q

What is Pharmacokinetics?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Why is pharmacokinetics important?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

4 Equations

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

One Compartment Model

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Two Compartment Model

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Linear Plot of Drug Concentration vs. Time

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Semi-Log Plot of Drug Concentration vs. Time

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Apparent Volume of Distribution Equation

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Apparent Volume of Distribution Definition

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Vd and Tissue vs. Plasma Binding

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Patients and Vd

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Parameters for Drug Correction

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Skin and Estimating Vd

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Obese Patients vs. Patients with Edema

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

[Drug] vs. Time and First Order Kinetics

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Elimination Rate Constant Equation

17
Q

Drug with 0 Order Kinetics

18
Q

First Order Kinetics vs. Saturating Kinetics (0 Order Kinetics)

19
Q

Clearance Equation

20
Q

Definition of Clearance

21
Q

Fast Acetylators vs. Slow Acetylators

22
Q

Affect of Clearance on Age

23
Q

Bioavailability Equation

24
Q

Definition of Bioavailability

25
Q

3 Important Parameters of Oral Drug Concentration

26
Q

Bioequivalence

27
Q

Bioequivalence vs. Bioavailability

28
Q

Absorption and Half Life

29
Q

Approach to Solving PK Problems

32
Q

Determine Vd and K

33
Q

Clearance Definition