Membrane Transport Proteins Flashcards
Lecture Overview

Ions In Plasma

Patient with Hypoatremia
Patient with Hypoatremia — low sodium
IV correction leads to Central pontine Mylenosis*sp
Effects of Isotonic, Hypertonic, and Hypotonic Solutions on Cell Volume

Osmotic Pressure

Phospholipid Bilayer

Components of the Phospholipid bilayer

Trends in intracellular vs. Extracellular Ion Concentration

Relative Permeability to various Ions and Molecules of Phospholipid Bilayer

Overview of Membrane Transport Proteins

Simple Diffusion

Facilitated Transport

Active Transport

Co-Transport

Simple Diffusion through Membrane Bilayer

Key Points of Simple Diffusion

Facilitated Transport

Frog Oocytes and Aquaporins

Structure of Aquaporin

Key Points of Facilitated Diffusion

P-Class Pumps

V-Class Proton Pumps

F-Class Pumps

ABC Superfamily Pumps

4 Types of ATP Pumps
P-Class
V-Class
F-Class
ABC Superfamily
Transcellular Transport of Glucose from the Intestinal Lumen

Key Points of Active Transport

Co-Transport
Secondary Active Transport

Key Points of Cotransport

Multidrug Transporter ABCB1

Selected Human ABC Proteins

ATPase and pH

Non-Gated Channels and Resting Membrane Potential

If we introduce large pores what will happen?


What will introducing this pump ultimately do?


What will happen once we produce a Potassium Channel?


ABC Proteins and Multi-Drug Resistence
