World Assessment: block3 Flashcards
alveolar hyaline membrane formation
acute respiratory distress syndrome
Pulmonary endothelial dysfunction
pulmonary hypertension
macrophages with accumulated PAS positive granules in GI suggest
Whipple disease
GI mucosal hemorrhage and patchy areas of necrosis
early ischemic colitis
Hypoglycemia after prolonged fasting with inapproprirately low ketone bodies suggest
impaired beta-oxidaiton
Most common defect in beta oxidation
- medium chain acyl-CoA dehydrogenase deficiency
What does RAS do
GTP-binding, signal transducing oncoprotein
what is the y intercept for line weaver-burk plot
1/Vmax
what is the x intercept for line weaver burn plot
1/-Km
osteoarthritis is most common risk factor
age
what can carcinoid syndrome ( flushing, diarrhea) be treated with
octreotide
MOA for octreotide
Somatostatin analog
- inhibits release of bioactive peptides by carcinoid tumor
what organism has haploid genome, peptidoglycan cell wall sandwiched between an outer membrane and an inner plasma membrane
gram negative bacteria
MOA for Thiazolidinediones
peroxisome proliferator-activated receptor- gamma agonist
- increase insulin sensitivity
PE shows area of fluctuant with overlying erythema near the perineum. indicates
crowns disease
how is hepatic encephalopathy treated
- lactulase : acidifies contents of GI
- Rifaximin or neomycin : decreaes NH4+ producing bacteria
how does cAMP relax bronchial smooth muscle
inhibit myosin phosphorylation and lowering of the intracellular calcium concentraiton
pathogenesis of osteomalacia
decrease mineralization of newly deposited osteoid
patchy nerve demyelination refers to
multiple sclerosis
difference between arterial atheroscloeriss and diabetic neuropathy
arterial atherosclerosis is more exertion symptoms
Li-Fraumeni syndrome is mutation in
p53 tumor suppressor gene
Recurrent laryngeal nerve branch off the vagus nerves innervates all intrinsic muscles of larynx that are responsible for what, exception
sound production
- cricothyroid
where does papillomavirusues replicate
host cell nucleas
where does poxvirus replicate
do no replicate in host cell membrane
lymphocytic infiltration of thyroid gland with follicular destruction and germinal center formation. Hurthle cells
Hashimotos thyroidits
ASD is associated with what kind of splitting
fixed spitting
Intellectualization
excessive thinking to avoid painful emotions or fears
Acute-onset anemia in male of african , asian, or mediterranean descent being treated with sulfonamide has what most likely RBC problem
- glucose-6-phosphate dehydrogenase deficiency
what happens to GFR and RPF in contriction of efferent vessel in kidney
increase GFR
- decrease RPF
what are the unmyelinated fibers in neurosn
Afferent: slow pain, heat sensation, olfaction
efferent: postganglionic automonic neurons
standard error
measure of variability around the mean
- larger sample size smaller SE
genome for reovirus
double-stranded RNA
genome for picornaviriae
positive sense single stranded RNA
during antigen processing in macrophages, what is associated protein
invariant chain
during MHC1 class I prevention, what is associated protein
Beta2- microglobulin
reduced taste sensation, burning sensation in mouth an lip dryness is seen in what anemia
iron
what is the pathology causing reactive arthritis
deposition of immune complexes