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Uworld > World Assessment: block3 > Flashcards

World Assessment: block3 Flashcards

1
Q

alveolar hyaline membrane formation

A

acute respiratory distress syndrome

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2
Q

Pulmonary endothelial dysfunction

A

pulmonary hypertension

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3
Q

macrophages with accumulated PAS positive granules in GI suggest

A

Whipple disease

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4
Q

GI mucosal hemorrhage and patchy areas of necrosis

A

early ischemic colitis

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5
Q

Hypoglycemia after prolonged fasting with inapproprirately low ketone bodies suggest

A

impaired beta-oxidaiton

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6
Q

Most common defect in beta oxidation

A
  • medium chain acyl-CoA dehydrogenase deficiency
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7
Q

What does RAS do

A

GTP-binding, signal transducing oncoprotein

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8
Q

what is the y intercept for line weaver-burk plot

A

1/Vmax

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9
Q

what is the x intercept for line weaver burn plot

A

1/-Km

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10
Q

osteoarthritis is most common risk factor

A

age

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11
Q

what can carcinoid syndrome ( flushing, diarrhea) be treated with

A

octreotide

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12
Q

MOA for octreotide

A

Somatostatin analog

- inhibits release of bioactive peptides by carcinoid tumor

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13
Q

what organism has haploid genome, peptidoglycan cell wall sandwiched between an outer membrane and an inner plasma membrane

A

gram negative bacteria

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14
Q

MOA for Thiazolidinediones

A

peroxisome proliferator-activated receptor- gamma agonist

- increase insulin sensitivity

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15
Q

PE shows area of fluctuant with overlying erythema near the perineum. indicates

A

crowns disease

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16
Q

how is hepatic encephalopathy treated

A
  • lactulase : acidifies contents of GI

- Rifaximin or neomycin : decreaes NH4+ producing bacteria

17
Q

how does cAMP relax bronchial smooth muscle

A

inhibit myosin phosphorylation and lowering of the intracellular calcium concentraiton

18
Q

pathogenesis of osteomalacia

A

decrease mineralization of newly deposited osteoid

19
Q

patchy nerve demyelination refers to

A

multiple sclerosis

20
Q

difference between arterial atheroscloeriss and diabetic neuropathy

A

arterial atherosclerosis is more exertion symptoms

21
Q

Li-Fraumeni syndrome is mutation in

A

p53 tumor suppressor gene

22
Q

Recurrent laryngeal nerve branch off the vagus nerves innervates all intrinsic muscles of larynx that are responsible for what, exception

A

sound production

- cricothyroid

23
Q

where does papillomavirusues replicate

A

host cell nucleas

24
Q

where does poxvirus replicate

A

do no replicate in host cell membrane

25
Q

lymphocytic infiltration of thyroid gland with follicular destruction and germinal center formation. Hurthle cells

A

Hashimotos thyroidits

26
Q

ASD is associated with what kind of splitting

A

fixed spitting

27
Q

Intellectualization

A

excessive thinking to avoid painful emotions or fears

28
Q

Acute-onset anemia in male of african , asian, or mediterranean descent being treated with sulfonamide has what most likely RBC problem

A
  • glucose-6-phosphate dehydrogenase deficiency
29
Q

what happens to GFR and RPF in contriction of efferent vessel in kidney

A

increase GFR

- decrease RPF

30
Q

what are the unmyelinated fibers in neurosn

A

Afferent: slow pain, heat sensation, olfaction
efferent: postganglionic automonic neurons

31
Q

standard error

A

measure of variability around the mean

- larger sample size smaller SE

32
Q

genome for reovirus

A

double-stranded RNA

33
Q

genome for picornaviriae

A

positive sense single stranded RNA

34
Q

during antigen processing in macrophages, what is associated protein

A

invariant chain

35
Q

during MHC1 class I prevention, what is associated protein

A

Beta2- microglobulin

36
Q

reduced taste sensation, burning sensation in mouth an lip dryness is seen in what anemia

A

iron

37
Q

what is the pathology causing reactive arthritis

A

deposition of immune complexes

Uworld (63 decks)

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