Test 61: all Flashcards

1
Q

3 year old, has: intellectual disability, gait or posture abnormality, eczema, and musty body odor

A

phenylketonuria

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2
Q

What is X-linked (Bruton) agammaglobulinemia ? mutation in what

A

defect in B cell maturation

- Burton tyrosine kinase gene

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3
Q

Staph. aureus in an IV drug user hurts what valve

A

tricuspid valve

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4
Q

Absolute risk reduction equation

A

event rate in the central group - event rate in treatment group

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5
Q

patient presenting with skeletal abnormalities, lens dislocation, intellectual deficits, vascular thrombosis and genetic defect in cystathionine beta-synthase enzyme

A

Homocystinuria

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6
Q

Pleiotrophy

A

multiple phenotypic manifestations result from single genetic mutation

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7
Q

When do children develop an understanding of concept of gender

A

age 3-4

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8
Q

first line therapy for Lyme disease? contraindications?

A

Doxycycline - contraindicated in pregnancy due to tooth discoloration
- give Amoxicillin

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9
Q

Burkitt lymphoma and nasopharyngeal carcinoma is related to what virus

A

EBV

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10
Q

Postauricular and occipital lymphadenopathy is common in what virus

A

rubella, togavirus

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11
Q

What does pyruvate kinase convert

A

Phosphoenolpyruvate to pyruvate

- generate ATP

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12
Q

Role of splenic red pulp

A

remove damaged RBC

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13
Q

what values are changed due to sickling episodes that result in hemolysis

A
  • increase indirect bilirubin and lactate dehydrogenase

- decrease levels of haptoglobin

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14
Q

Where are dietary lipids digested

A

duodenum

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15
Q

where are fatty acids passively absorbed

A

jejunum

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16
Q

SLE impact on complement

A

reduce rerum complement levels

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17
Q

Anti-cyclic citrullinated peptide antibodies are found in what

A

rheumatoid artheritis

18
Q

About half is sudden infant death syndrome is due to what

A

tobacco exposure

19
Q

What runs through the hepatoduodenal ligament

A

portal triad

20
Q

Pringle maneuver: occlusion of portal triad to distinguish the source of right upper quadrant bleeding. If bleeding persists, what is the source of blood

A
  1. inferior vena cava or hepatic veins
21
Q

LH stimulates what in the ovaries

A

-theca internal cells, produce androgens

22
Q

What does FSH do in ovaries

A

converts androgen to estrogen via aromatase

23
Q

What type of drug is Buspirone and MOA

A
  • nonbenzodiazepine anxiolytic

- stimulates 5-HT1a receptors

24
Q

How long does it take for Buspirone to work

A

slow onset

25
Q

Location of Wernicke area and what supplies it

A

superior temporal gyrus of temporal lobe

- middle meningeal artery

26
Q

viridans streptococci dextrans adhere to what molecule

A

fibrin-platelet aggregates

27
Q

If the patient cannot make a decision and has not prepared an advance directive, who do you listen to

A
  1. spouse
  2. adult children
  3. parents
  4. adult siblings
28
Q

Goodpasture has antibodies against what

A

collagen type IV in lung or kidney

29
Q

drug that causes arteriolar dilation, improves renal perfusion, and increases natriuresis in the case of hypertension

A

Fenoldapam

30
Q

MOA of Fenoldapam

A

dopamine-1 receptor agonist

31
Q

most gastric ulcers occur where in stomach

A

lesser curvature of stomach

32
Q

what artery runs along the lesser curvature of stomach

A

left and right gastric arteries

33
Q

damage to what pleura can cause phrenic nerve irriation

A

diaphragmatic pleura and mediastinal pleura

34
Q

familial dysbetalipoproteinemia have what serum levels

A

increase cholesterol and triglyceride levels

35
Q

What is defected in dysbetalipoproteinemia

A

ApoE3 and ApoD4 levels

36
Q

Communicating hydroceles and indirect hernias are caused by what

A

incomplete obliteration of processus vaginalis

37
Q

What is the homophiles influenza’s capsule made out of

A

polyribosylribitol phosphate

38
Q

Side effects of Ethambutol

A

optic neuropathy: color blindess, central scotoma, and decreased visual acuity

39
Q

which side is the inferior vena cava to the vertebra

A

right to the vertebral body

40
Q

At what level do the renal veins join in the IVC

A

L1/L2

41
Q

at what level do the common iliac veins merge with IVD

A

level of L4