Test 61: all Flashcards
3 year old, has: intellectual disability, gait or posture abnormality, eczema, and musty body odor
phenylketonuria
What is X-linked (Bruton) agammaglobulinemia ? mutation in what
defect in B cell maturation
- Burton tyrosine kinase gene
Staph. aureus in an IV drug user hurts what valve
tricuspid valve
Absolute risk reduction equation
event rate in the central group - event rate in treatment group
patient presenting with skeletal abnormalities, lens dislocation, intellectual deficits, vascular thrombosis and genetic defect in cystathionine beta-synthase enzyme
Homocystinuria
Pleiotrophy
multiple phenotypic manifestations result from single genetic mutation
When do children develop an understanding of concept of gender
age 3-4
first line therapy for Lyme disease? contraindications?
Doxycycline - contraindicated in pregnancy due to tooth discoloration
- give Amoxicillin
Burkitt lymphoma and nasopharyngeal carcinoma is related to what virus
EBV
Postauricular and occipital lymphadenopathy is common in what virus
rubella, togavirus
What does pyruvate kinase convert
Phosphoenolpyruvate to pyruvate
- generate ATP
Role of splenic red pulp
remove damaged RBC
what values are changed due to sickling episodes that result in hemolysis
- increase indirect bilirubin and lactate dehydrogenase
- decrease levels of haptoglobin
Where are dietary lipids digested
duodenum
where are fatty acids passively absorbed
jejunum
SLE impact on complement
reduce rerum complement levels
Anti-cyclic citrullinated peptide antibodies are found in what
rheumatoid artheritis
About half is sudden infant death syndrome is due to what
tobacco exposure
What runs through the hepatoduodenal ligament
portal triad
Pringle maneuver: occlusion of portal triad to distinguish the source of right upper quadrant bleeding. If bleeding persists, what is the source of blood
- inferior vena cava or hepatic veins
LH stimulates what in the ovaries
-theca internal cells, produce androgens
What does FSH do in ovaries
converts androgen to estrogen via aromatase
What type of drug is Buspirone and MOA
- nonbenzodiazepine anxiolytic
- stimulates 5-HT1a receptors
How long does it take for Buspirone to work
slow onset
Location of Wernicke area and what supplies it
superior temporal gyrus of temporal lobe
- middle meningeal artery
viridans streptococci dextrans adhere to what molecule
fibrin-platelet aggregates
If the patient cannot make a decision and has not prepared an advance directive, who do you listen to
- spouse
- adult children
- parents
- adult siblings
Goodpasture has antibodies against what
collagen type IV in lung or kidney
drug that causes arteriolar dilation, improves renal perfusion, and increases natriuresis in the case of hypertension
Fenoldapam
MOA of Fenoldapam
dopamine-1 receptor agonist
most gastric ulcers occur where in stomach
lesser curvature of stomach
what artery runs along the lesser curvature of stomach
left and right gastric arteries
damage to what pleura can cause phrenic nerve irriation
diaphragmatic pleura and mediastinal pleura
familial dysbetalipoproteinemia have what serum levels
increase cholesterol and triglyceride levels
What is defected in dysbetalipoproteinemia
ApoE3 and ApoD4 levels
Communicating hydroceles and indirect hernias are caused by what
incomplete obliteration of processus vaginalis
What is the homophiles influenza’s capsule made out of
polyribosylribitol phosphate
Side effects of Ethambutol
optic neuropathy: color blindess, central scotoma, and decreased visual acuity
which side is the inferior vena cava to the vertebra
right to the vertebral body
At what level do the renal veins join in the IVC
L1/L2
at what level do the common iliac veins merge with IVD
level of L4
