test 55: ALL

Question 1

2 subastances what drive angiogenesis

Answer 1

1. VEGF: vascular endothelial growth factor

2. FGF: fibroblast growth factor

Question 2

Erythematous, itchy breast rash with skin texture changes analogous to an orange peal is what? disease?

Answer 2

• Peau d’ orange

- inflammatory breast cancer

Question 3

Most common inherited cause of intellectual disability

Answer 3

Fragile X syndrome

Question 4

3 things found in Hep A liver biospry

Answer 4

1. hepatocyte swelling
2. monocyte infiltration
3. councilman bodies

Question 5

clinical feature of Hep A

Answer 5

usually asymptomatic

• fever
• anorexia
• dark-colored urine

Question 6

In the presence of oxygen, what does pyruvate get converted to

Answer 6

Acetyl-CoA via pyruvate dehydrogenase.

Question 7

patient show neurologic symptoms ( tingling, difficulty concentrating) and recurrent episodes of nonspecific abdominal pain has what

Answer 7

acute intermittent porphyria

Question 8

what accumulates in acute intermittent porphyria

Answer 8

• delta aminolevulinic acid

- prophobilinogen (PBG)

Question 9

what secretes Secretin

Answer 9

duodenal S-cells

Question 10

when does secretin get secreted

Answer 10

• increasing [H+]

Question 11

what are the effects of Secretin

Answer 11

• increases pancreatic bicarbonate secretion

- [Cl-] content of pancreatic secretions decrease in proportion to [bicarbonate] increases

Question 12

anterior nasal septum contains what structure

Answer 12

Kiesselbach plexus

Question 13

equation for FF ( filtration fraction)

Answer 13

GFR/ Renal plasma flow

Question 14

How do AV shunts impact preload and after load

Answer 14

preload: increase
afterload: decrease

Question 15

name 2 critera for ADHD

Answer 15

1. before age 12

2. greater than or equal 6 inattentive and/or hyperactive/ impulsive symptoms

Question 16

Axillary lymph node dissection is risk factor for the development of what

Answer 16

chronic lymphadema –> angiosarcoma

Question 17

What is Chediak-Higashi syndrome

Answer 17

autosomal recessive disorder of neutrophil phagosome lysosome fusion

Question 18

clinical features of Chediak-Higashi syndrome

Answer 18

• neurological abnormalities
• partial albinism
• defective neutrophil function

Question 19

What goes wrong in Albinism

Answer 19

• production of pigment itself is defective,

- melanocytes are normal in number and location

Question 20

DiGeroge Syndrome is a deletion on what chromosome

Answer 20

22

Question 21

regardless of patient’s hydration status, majority of water reabsorption in the nephron occurs where

Answer 21

proximal tubules

Question 22

What is the patient requirement for considering hospice care

Answer 22

• with metastatic cancer or other terminal illness

- and life expectancy of less than 6 months

Question 23

patient has ridid abdomem with associated left shoulder pain, hypotension and tachycardia suggets

Answer 23

splenic laceration

Question 24

Any abdominal process ( ex. ruptured spleen) irritating the phrenic nerve sensory fibers around the diaphragm can cause what

Answer 24

referred pain to C3-C5 shoulder region ( Kehr sign)

Question 25

Adenomyosis

Answer 25

endometrial glandular tissue within the myometrium

Question 26

endometrial hyperplasia

Answer 26

• abnormal endometrial gland proliferation

Question 27

trochlear nerve innervates wht

Answer 27

superior oblique muscle

Question 28

The symptoms for acute intermittent porphyria

Answer 28

5 P’s

• Painful abdomen
• Port wine - colored urine
• Polyneuropathy
• psychological disturbances
• Precipitated by drugs