World assessment: Block 1 Flashcards
what causes acute respiratory distress syndrome
SPARTAS
- sepsis
- pancreatitis
- pneumonia
- aspiration
- uRemia
- rauma
- amniotic fluid embolism
- shock
patient has recent trauma, new diffuse symmetric pulmonary opacities, and normal sized hearth
acute respiratory distress syndrome
pathology of acute respiratory distress syndrome
- injury of endothelial
- increase alveolar capillary permeability
- fluid into alveolar
- activate neutrophils
- damage type I and II pneumocytes
osteosarcoma
malignant proliferation of osteoblasts
Paget is related to what other tumor of the bone
osteosarcoma
Globus sensation
feeling of a “lump in the throat” without accompanying physical, endoscopic, or radiologic findings of esophageal obstruction
what type of crystals form in gout
- monosodium urate crystals
- negatively birefringent
Endometriosis
presence of endometrial glands and stroma outside the uterus
Most common site for endomeriosis
ovary
Adenomyosis
extension of endometrial tissue into uterine myometrium
Leiomyoma
benign smooth muscle tumor of uterus
which vitamin is highly teratogenic especially during the first trimester of pregnancy
- vitamin A
MOA for Oseltamivir
inhibits neuraminidase
appearance of DNA fragments in multiples of 180 base pairs on gel electrophoresis indicates
DNA laddering - apoptosis
follicular B cell lymphoma overexposes what oncogene
BCL2
Methylphenidate is related to what drug
- amphetamines
Germline mosaicism
presence of multiple, genetically different gamete cell lines
- genetic mutation in offspring but not in parents
pleiotropy
1 gene type contributes to multiple phenotypes
Diabetic patients should do what everyday
inspect their feet
Auer rods are azurophilic, needle-shaped cytoplasmic inclusions that found in
acute promeylocytic leukemia
15:;17
who is the only person to secrete IL-2
T lymphocytes
Cadherins
- calcium-dependent molecules that bind epithelial cells together within tissues
Caherin molecules on epithelial cells bind to cadherin molecules on adjacent cells to form
- adherens junction
2. desmosomes
cell adhesion to basement membrane
hemidesmosomes
characterize Molluscum contagiousm
umbilicated, flesh-colored papules on skin and mucous membranes
histo for molluscum contagiousum
- eosinophilic cytoplasmic inclusion bodies
primary concern with both anterior and posterior dislocations of knee joint
popliteal artery
Sublimation
mature defense mechanism in which person channels unacceptable thoughts or impulses into socially acceptable behavior
reaction formation
replacing a warded-off idea or feeling by an emphasis on the opposite
Projection
misunderstanding another feelings and acting externally to it
Ligand binding to tyrosine kinase receptor results in formation of what
receptor dimers and conformational change that exposes tyrosine kinase-active sites
Sildenafil works on what muscle
corpora cavernosa
Eye problem with craniopharyngioma
bitemporal hemianopia
ion flow rate for pancreatic exocrine
high
low
low: more bicarb
high: more chloride
Difference between acute distress disorder and post traumatic stress disrocer
- ASD: 3 days - 1 month
Schizophrenia all diseases
- Schizophrenia : 6 months
- Brief psychotic disorder: less than 1 month
- Schizophreniform: 1- 6 months
false positive rate
1- specificity
what is wrong in acute intermittent porphyria ? what does it convert
prophobilinogen deaminase
- prophobilinogen to hydroxymethylbilane