VO11.1 Flashcards

1
Q

waardoor kan een souffle over de schildklier komen?

A

sterke doorbloeding

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2
Q

welk LO typerend voor ZvG

A
  • diffuse vergroting
  • verhoogde perfusie
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3
Q

is er bij thyreoiditis sprake van struma?

A

nee, want weefseldestructie

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4
Q

prolactinoom behandeling

A

dopamine agonisten want dat remt de aanmaak van prolactine

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5
Q

bij pan-hypopituItarisme behandeling volgorde

A

eerst hydrocortison en daarna pas L-thyroxine, anders tekort aan cortisol (L-thyroxine verhoogt het metabolisme); addisonse crisis

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6
Q

TRbeta functie

A

negatieve feedback door binding van T4

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7
Q

TRbeta mutatie

A

minder negatieve feedback, TSH stimulering, schildklierstimulering en meer schildklierhormoon

klachten van een hypo

er heerst een hyperthyreoidie in weefsels met TFalfa

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8
Q

TRbeta locaties

A
  • lever
  • hypothalamus
  • hypofyse
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9
Q

TRalfa locaties

A

hart

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10
Q

betablokkers invloed op schildklierhormoon

A

remt omzetting van T4 –> T3

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11
Q

prolactine invloed LH/FSH

A

remmend

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12
Q

TSH over placenta?

A

nee

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13
Q

T4/L-thyroxine over placenta?

A

ja

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14
Q

antistoffen over placenta?

A

ja

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15
Q

medicatie over placenta?

A

ja

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16
Q

L-thyroxine zwangerschap

A

ophogen 25-50%

17
Q

waarom neemt T4 verbruik bij moeder toe eerste trimester?

A

foetus is daarvan afhankelijk

18
Q
A