Topic 12: Cardiovascular System - Blood (CT) + RBC Flashcards
What are 4 characteristics of blood?
- higher viscosity than H2O
- 37 degrees C
- pH 7.35-7.45
- 4-6 L in an adult
What are the two compositions of blood?
plasma - fluid portion with solutes
formed elements - cellular portion
What is plasma (matrix)?
- blood minus formed elements
What is plasma composed of? (3) give their percentages
90% water
8% protein
2% other solutes
What are the 3 proteins found in plasma?
- albumin
- fibrinogen
- globulin
What is the function of albumin?
- control tissue water balance
What is the function of fibrinogen?
- clot formation
What is the function of globulin?
antibodies
What other solutes are in plasma? (5)
- nutrients
- hormones
- wastes
- electrolytes
- gases
What are the formed elements of blood composed of? (3)
- RBC (erythrocytes)
- WBC (leokocytes)
- Platelets
What is hematocrit?
- percent of blood volume that is RBC (45%)
What are some characteristics of RBC? (4)
- biconcave disc shape
- anucleate when mature
- 120 day life span
- contain hemoglobin, a pigment protein
Where are RBC destroyed?
- liver and spleen
Hemoglobin contains heme. What is Heme? (3)
- red pigment
- contains iron
- attaches and transports O2
in lecture, it is why blood is metallic tasting. If low O2 in cell, it will drop O2 there
Hemoglobin contains globin. What is globin?
- protein
- attaches and transports CO2
Heme is further broken down into ____
- bilirubin
in lecture, it makes urine yellow and feces brown
Globin is further broken down into ____
amino acids
What happens to the iron in heme? (2)
- Fe2+ is recycled or stored
- its always toxic so it is always bound to protein
