Chapter 7: The Blueprint of Life, from DNA to Protein: DNA intro Flashcards

1
Q

What is the central dogma of biology?

A
  • genetic info flows from DNA to RNA to protein, or RNA to protein
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2
Q

What is genetics the study of?

A
  • heredity
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3
Q

What is molecular biology?

A
  • the science dealing with NA and protein sysnthesis
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4
Q

What is a genome?

A
  • the total DNA contained in the cell
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5
Q

What does the genome consist of? (2)

A
  • chromosomes and any plasmids
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6
Q

What do chromosomes contain?

A
  • genes
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7
Q

What are genes?

A
  • sections of DNA that code for a functional product
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8
Q

What is DNA?

A

a macromolecule made of nucleotides

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9
Q

Each DNA nucleotide consists of? (3)

A
  • nitrogenous base (ATGC)
  • sugar (deoxyribose, labelled 1’ to 5’)
  • phosphate
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10
Q

How is DNA in a double helix shape?

A
  • two strands held together by hydrogen bonds between bases
  • note base pairing rule (A to T, G to C)
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10
Q

How is DNA in a double helix shape? (3)

A
  • two strands held together by hydrogen bonds between bases
  • note base pairing rule (A to T, G to C)
  • antiparallel
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11
Q

Strands of DNA are complementary, which means what?

A
  • sequence of one strand determines the sequence of the other
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12
Q

Who discovered the double helix shape?

A

Watson and Crick

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13
Q

The nucleotides in DNA are held together by what type of bonds?

A
  • phosphodiester bonds
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14
Q

How do the nucleotides of DNA join togethr?

A
  • 5’ carbon of one nucleotide is joined to a 3’ carbon of the next nucleotide, with a phosphate between them
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15
Q

What direction do we usually consider DNA?

A

5’ to 3’ direction
- starting at 5’ end
- finishing at 3’ end

16
Q

What direction is the leading strand of DNA?

A
  • 5’ to 3’
17
Q

What direction is the lagging strand of DNA?

A

3’ to 5’

18
Q

What order is the flow of genetic information?

A
  1. replication
  2. Gene expression
  3. Recombination
19
Q

What occurs in replication?

A
  • DNA is copied before cell division
20
Q

What occurs in gene expression?

A
  • DNA is used to make proteins
21
Q

What occurs in recombination?

A
  • DNA can flow between two different bacterial cells