Chapter 5: Control of Microbial Growth - Chemicals (Alcohols, Metals, QUATS, etc.) Flashcards

1
Q

How does alcohol work? (2)

A
  • denatures proteins and disrupts membranes
  • acts quickly and evamporates
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2
Q

What microbes does alcohol kill? What does it not kill? (2 and 2

A
  • bacteria and fungi
  • does not kill endospores and some viruses
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3
Q

Where is alcohol used on? (2)

A
  • surfaces in a lab
  • degerm skin
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4
Q

Is alcohol an adequate antiseptic? Why or Why not? (2)

A
  • no
  • often combined with other chemicals to increase effectiveness
  • citric acid or urea, isopropyl
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5
Q

What are 2 types of alcohol?

A
  • ethanol - 70% most effective
  • isopropanol rubbing alcohol
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6
Q

Why are heavy metals used on microbes?

A
  • copper, silver, zinc and mercury can inhibit microbes
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7
Q

How does SILVER NITRATE (1%) affect microbes? In other words, when is it used? (1)

A
  • used as eyedrops for new-born infants to protect agents gonorrheal opthalmia
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8
Q

When is silver sulfadiazine used?

A
  • in topical creams for burns
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9
Q

Why are silver ions used in some bandages and catheters?

A
  • it slows the growth of microbes
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10
Q

When is copper sulfate used to control microbes?

A
  • inhibits algae in reservoirs
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11
Q

When is mercuric chloride used to control microbes?

A
  • used in paint to control mildew
    very toxic cuz it has mercury
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12
Q

When is zinc chloride used to control microbes?

A
  • used as an antiseptic in mouthwashes
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13
Q

Are soap and detergents disinfectants or antiseptics?

A
  • neither
  • works to degerm skin
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14
Q

Why is soap and detergent important?

A
  • important in mechanical removal of microbes
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15
Q

How do soaps/detergents work? (2)

A
  1. soap breaks up oily deposits and film (ex. on skin)
  2. water can then wash these deposits away, along with microbes
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16
Q

What are quaternary ammonium compounds (quats)? (2)

A
  • cationic detergents
  • strongly antimicrobial colorless, tasteless, odorless, and non-toxic at low concentrations
17
Q

What microbes do quats kill/not kill? (3)

A
  • kills most bacteria, fungi, and some viruses
  • does not kill endospores
  • does not kill some gram - bacteria
18
Q

Give an example of a quat, and what it is used for.

A
  • cepacol
  • used as a mouthwash
19
Q

Some gram negative bacteria not only survive, but grow well on Quats. Give an example of one, and include what infection it causes

A
  • Pseudomonas aeruginosa
  • cause of burn infections
20
Q

What are gaseous chemosterilizers?

A
  • chemical gasses used for sterilization
21
Q

What chemical is a gaseous chemosterilizer?

A
  • Ethylene oxide
22
Q

How does ethylene oxide work? (2)

A
  • denatures proteins
  • germicidal
  • requires 4-18 hours of exposure
23
Q

What microbes does ethylene oxide kill?

A
  • ALL of them
  • including endospores and viruses
24
Q

Can ethylene oxide pass through plastics?

A
  • yes, it is highly penetrating
25
Q

What is ethylene oxide used to sterilize?

A
  • disposable hospital equipment and lab suppies
  • ex. plastic tubing
  • disposable swabs
26
Q

How do oxidizing agents work?

A
  • oxidizes and denatures proteins
27
Q

Oxidizing agents are useful against ____ organisms

A

anaerobic organisms
in lecture, its bc these organisms lack enzymes to survive

28
Q

Name 3 common oxidizing agents

A
  1. hydrogen peroxide
  2. ozone
  3. benzoyl peroxide
29
Q

What is hydrogen peroxide used on?

A
  • common antiseptic for wounds
30
Q

What is ozone used for?

A
  • used with chlorine to disinfect water
31
Q

What is benzoyl peroxide used for? (2)

A
  • used as an antiseptic on skin
  • kills anaerobic bacteria living in tissues
    ex. Bacteria that causes acne