Chapter 13: Viruses - Essential structure Flashcards

1
Q

What are viruses?

A
  • Acellular particles capable of infecting host cells and causing disease
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2
Q

What does it mean by viruses are not free-living?

A
  • they require a host cell in which to multiply
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3
Q

Obligate intracellular parasites are a type of virus. What do they do?

A
  • use host metabolic systems and usually disrupt normal host cell function
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4
Q

What are characteristics of viruses? (5)

A
  1. Acellular
  2. do not have a plasma membrane
  3. contains a single type of nucleic acid (DNA or RNA)
  4. surrounded by a protein coat
  5. May or may not have additional envelope of lipids
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5
Q

Do viruses have enzymes?

A

have very few of their own, but they take enzymes of their host

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6
Q

In lecture, what type of viruses are more prone to degradation?

A
  • envelope viruses
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7
Q

What kind of organisms can viruses effect? (5)

A
  • animals
  • plants
  • fungi
  • protozoa
  • bacteria
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8
Q

Most viruses are specific for a single host species. What does this mean?

A
  • To infect a cell, the virus must recognize features on the host cell surface
    ex. some viruses recognize the fimbriae of a certain bacterial species
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9
Q

What type of microscope must be used to view viruses?

A
  • electron microscopes
  • range from 20-1000 nm in length
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10
Q

What three parts do viruses have?

A
  • nucleic acid
  • capsid
  • envelope
    note that viruses need at least 2 of these
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11
Q

Can viruses have both DNA and RNA?

A

no

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12
Q

What can the nucleic acid in viruses be?

A
  • single stranded or double stranded
  • linear or circular
  • can be in several pieces - segmented
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13
Q

What is the total amount of nucleic acid in a virus

A
  • a few thousand to 250 000 base pairs
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14
Q

How many base pairs does the E. coli chromosome have?

A

4.6 million

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15
Q

What is a capsid? (2)

A
  • protein coat surrounding the nucleic acid
  • made up of individual proteins called capsomeres
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16
Q

What is a nucleocapsid?

A
  • nucleic acid and capsid
  • minimum required structure for a virus
17
Q

What is an envelope?

A
  • lipid bilayer (membrane) acquired from the host cell
  • external coating around the nucleocapsid
18
Q

Are envelopes present in all viruses?

A

no

19
Q

What are spikes in an envelope?

A

additional viral proteins inserted into envelope